Related Experiment Video
Updated: Feb 9, 2026
07:45
Acute Myocardial Infarction in Rats
Published on: February 16, 2011
54.7K
Association between Low Free Triiodothyronine Levels and Poor Prognosis in Patients with Acute ST-Elevation
Yuanbin Song1,2, Jiabei Li1,2, Shizhu Bian1
1Department of Cardiology, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China.
Biomed Research International
|June 1, 2018
Summary
Low free triiodothyronine (fT3) levels indicate a poorer prognosis for patients with ST-elevation myocardial infarction (STEMI). Measuring fT3 can help identify high-risk STEMI patients early.
Area of Science:
- Cardiology
- Endocrinology
- Clinical Medicine
Background:
- Low free triiodothyronine (fT3) is linked to poor outcomes in heart disease, but data for ST-elevation myocardial infarction (STEMI) in Chinese patients is scarce.
- Controversy exists regarding the prognostic value of fT3 in cardiovascular conditions.
Purpose of the Study:
- To investigate the association between fT3 levels and prognosis in STEMI patients.
- To determine if fT3 levels can predict adverse outcomes in STEMI.
Main Methods:
- A prospective observational study included 699 STEMI patients.
- Patients were categorized into low fT3 (<3.1 pmol/L) and normal fT3 (≥3.1 pmol/L) groups.
- Outcomes including all-cause death and major adverse cardiac events (MACE) were tracked for 1 year.
Main Results:
- The low fT3 group had significantly higher rates of all-cause death (39.1% vs. 8.5%) and MACE (58.7% vs. 15.6%) compared to the normal fT3 group (P < 0.001).
- Low fT3 levels were independently associated with increased 30-day and 1-year all-cause death and MACE.
- Hazard ratios indicated a significant risk increase for adverse events in patients with low fT3.
Conclusions:
- Low fT3 levels are strongly associated with poor prognosis in STEMI patients.
- fT3 measurement is a simple and potentially valuable tool for identifying high-risk STEMI individuals.
- This finding supports the clinical utility of assessing fT3 in STEMI management.
Related Concept Videos
03:12Freezing Point Depression and Boiling Point Elevation
40.4K
Boiling Point Elevation
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
40.4K
01:20Elevation of Intermediate Points on Vertical Curves
308
Vertical curves are essential in roadway design because they provide smooth transitions between varying roadway grades. Designing vertical curves involves calculating intermediate elevations and identifying the curve's highest or lowest point, which is essential for optimal roadway performance.Intermediate elevations on a vertical curve are determined using the tangent offset method. This method considers the initial elevation at the start of the curve, the grades, and the curve's geometry. The...
308
01:27Associative Learning
1.4K
Associative learning is a fundamental concept in behavioral psychology, wherein a connection is established between two stimuli or events, leading to a learned response. This process is critical in understanding how behaviors are acquired and modified. Conditioning, the mechanism through which associations are formed, can be divided into two main types: classical conditioning and operant conditioning, each elucidating different aspects of associative learning.
Classical conditioning, also known...
Classical conditioning, also known...
1.4K
01:21Association Areas of the Cortex
9.5K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
9.5K
01:29Leveling Effect
1.4K
In acid-base chemistry, the leveling effect refers to the limitation imposed by the solvent on the strength of acids and bases in solution. When a base stronger than the solvent's conjugate base is used, it deprotonates the solvent until the base is entirely consumed, making it ineffective against weaker acids. Conversely, an acid stronger than the solvent's conjugate acid protonates the solvent until the acid is depleted, rendering it ineffective against weaker bases. Essentially, the...
1.4K
01:19High-Level and Low-Level Awareness
785
Controlled processes in human consciousness represent high-alert mental states where individuals deliberately focus their attention on achieving specific goals. Controlled processes can be seen in situations like mastering new technology, where a person might become so absorbed that they ignore surrounding distractions. Such processes involve selective attention, requiring one to concentrate on particular elements of experience while disregarding others. These are governed by executive...
785