Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hormonal action controlling mammary activity.

L M Houdebine, J Djiane, I Dusanter-Fourt

    Journal of Dairy Science
    |February 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Diet-induced modifications to milk composition have long-term effects on offspring growth in rabbits.

    Journal of animal science·2017
    Same author

    Differences during the first lactation between cows cloned by somatic cell nuclear transfer and noncloned cows.

    Journal of dairy science·2016
    Same author

    Milk from dams fed an obesogenic diet combined with a high-fat/high-sugar diet induces long-term abnormal mammary gland development in the rabbit.

    Journal of animal science·2015
    Same author

    Viability and stress protection of chronic lymphoid leukemia cells involves overactivation of mitochondrial phosphoSTAT3Ser727.

    Cell death & disease·2014
    Same author

    Genetically modified animals from life-science, socio-economic and ethical perspectives: examining issues in an EU policy context.

    New biotechnology·2013
    Same author

    Rabbit milk protein genes: from mRNA identification to chromatin structure.

    Animal : an international journal of animal bioscience·2012
    Same journal

    Invited review: Manufacturing Whey Protein Colloidal Particles via Liquid Antisolvent Precipitation Method: Particle Formation Mechanism and Ingredient Functionality Aspects.

    Journal of dairy science·2026
    Same journal

    Colostrum programs early t lymphocyte-mediated immunity in neonatal dairy calves: effects of deprivation and preservation method on passive transfer and antigen-specific responses.

    Journal of dairy science·2026
    Same journal

    Functional Characterization and Application of Autochthonous Lactic Acid Bacteria from Chinese Kefir for Improved Fermented Milk Quality.

    Journal of dairy science·2026
    Same journal

    Distinct contributions of the Agr and LuxS quorum-sensing systems to stress tolerance, biofilm formation, and persistence of Staphylococcus aureus in dairy-processing environments.

    Journal of dairy science·2026
    Same journal

    Integrating automated body condition scores and lactation data via optimization algorithms for maximized milk revenue and minimized cost of delayed conception in dairy cows.

    Journal of dairy science·2026
    Same journal

    Assessing genotype by feed interactions for milk production traits in dairy cattle.

    Journal of dairy science·2026
    See all related articles

    Hormones like prolactin, glucocorticoids, and progesterone regulate mammary gland differentiation. Prolactin stimulates milk synthesis gene expression, while progesterone inhibits it, and glucocorticoids amplify prolactin

    Area of Science:

    • Molecular Endocrinology
    • Cell Biology
    • Gene Regulation

    Background:

    • Mammary gland differentiation involves cell proliferation and gene activation for milk synthesis.
    • Hormonal control of these processes is complex and not fully understood.
    • Key hormones include prolactin, glucocorticoids, and progesterone.

    Purpose of the Study:

    • To elucidate the detailed roles of hormones in mammary gland differentiation.
    • To understand the mechanisms by which prolactin regulates casein gene expression.
    • To investigate the modulatory effects of glucocorticoids and progesterone on prolactin's actions.

    Main Methods:

    • Analysis of gene transcription and messenger RNA (mRNA) stabilization.
    • Investigation of translational control mechanisms.

    Related Experiment Videos

  • Hormonal manipulation studies in mammary gland models.

    • Main Results:

    • Prolactin enhances milk synthesis by increasing casein gene transcription and mRNA stability.
    • Prolactin also promotes the translation of casein mRNA.
    • Glucocorticoids potentiate prolactin's effect on casein gene transcription.
    • Progesterone antagonizes prolactin's action on casein gene transcription.

    Conclusions:

    • Prolactin is a primary inducer of milk synthesis gene expression through transcriptional and translational regulation.
    • Glucocorticoids and progesterone act as key modulators of prolactin's effects on mammary gland gene expression.
    • Understanding these hormonal interactions is crucial for comprehending mammary gland development and function.