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Saliva as a Future Field in Psoriasis Research
Farah Asa'ad1, Marco Fiore2, Aniello Alfieri2
1Department of Biomedical, Surgical & Dental Sciences, University of Milan, 20122 Milan, Italy.
Biomed Research International
|June 12, 2018
Summary
Psoriasis patients lack reliable prognostic biomarkers for monitoring disease and treatment effectiveness. Saliva research shows potential, suggesting a combination of markers could improve predictions for psoriasis management.
Area of Science:
- Dermatology and Oral Medicine
Background:
- Psoriasis is a chronic inflammatory skin disease with numerous comorbidities, including periodontitis.
- Current prognostic biomarkers for monitoring disease progression and therapeutic effectiveness in psoriasis are lacking.
- No single biomarker has been identified as an independent prognostic factor for psoriasis.
Purpose of the Study:
- To review current knowledge on salivary biomarkers for psoriasis.
- To explore the potential of saliva analysis in predicting disease course and treatment response.
- To highlight the need for further research into salivary markers for psoriasis management.
Main Methods:
- Systematic review of existing literature on saliva research in psoriasis.
- Analysis of studies investigating various salivary markers and their correlation with psoriasis.
- Synthesis of findings regarding the diagnostic and prognostic potential of salivary biomarkers.
Main Results:
- Several salivary markers have been investigated for their association with psoriasis.
- No single salivary marker has proven to be an independent prognostic factor.
- Combinations of salivary markers may offer improved prognostic prediction for psoriasis patients.
Conclusions:
- Saliva holds promise as a source for identifying prognostic biomarkers in psoriasis.
- Further research is essential to validate salivary biomarkers for disease monitoring and therapeutic effectiveness.
- A multi-marker approach in saliva analysis could enhance the management of patients with psoriasis.
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