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Related Experiment Video

Updated: Feb 9, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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Syncope and Headache.

Ramesh K Khurana1

  • 1Department of Medicine, MedStar Union Memorial Hospital, 201 East University Parkway, Baltimore, MD, 21218, USA. lyn.camire@medstar.net.

Current Pain and Headache Reports
|June 16, 2018
PubMed
Summary
This summary is machine-generated.

Headache associated with syncope is gaining attention. This review covers orthostatic hypotension-induced coat-hanger ache and migraine-related syncope, offering clinical insights into these conditions.

Keywords:
BaroreflexCoat-hanger acheNeurally mediated hypotensionOrthostatic hypotensionReflex syncope

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Area of Science:

  • Neurology
  • Cardiology

Background:

  • Syncope and headache are common symptoms with overlapping etiologies.
  • Recent interest focuses on the relationship between headache and syncope, particularly within the spectrum of orthostatic intolerance.

Purpose of the Study:

  • To review the existing literature on the co-occurrence of syncope and headache.
  • To share clinical experience and insights regarding these related conditions.

Main Methods:

  • Literature review of studies investigating syncope and headache.
  • Clinical experience-based observations and case discussions.

Main Results:

  • Orthostatic intolerance encompasses orthostatic hypotension (OH), neurally mediated hypotension (NMH), and postural tachycardia syndrome (PoTS).
  • Headache in OH, termed coat-hanger ache (CHA), presents in the neck and shoulders and can be a warning sign and treatment indicator.
  • Headache in NMH is less defined, with some studies linking migraine to syncope and suggesting short-duration headaches in laboratory settings.

Conclusions:

  • Understanding the specific headache patterns associated with different types of syncope, such as CHA in OH and migraine in NMH, is crucial for accurate diagnosis and management.
  • Clinical awareness of these headache-syncope associations can guide appropriate diagnostic testing and treatment strategies.