Related Experiment Video
Updated: Feb 8, 2026

In Vitro Thrombosis Test for Ventricular Assist Devices
Published on: March 21, 2025
Device Management and Flow Optimization on Left Ventricular Assist Device Support
Inna Tchoukina1, Melissa C Smallfield1, Keyur B Shah1
1Division of Cardiology, Department of Internal Medicine, Advanced Heart Failure and Transplantation, The Pauley Heart Center, Virginia Commonwealth University, 1200 East Broad Street, P.O. Box 980204, Richmond, VA 23298-0204, USA.
Abstract:
The authors discuss principles of continuous flow left ventricular assist device (LVAD) operation, basic differences between the axial and centrifugal flow designs and hemodynamic performance, normal LVAD physiology, and device interaction with the heart. Systematic interpretation of LVAD parameters and recognition of abnormal patterns of flow and pulsatility on the device interrogation are necessary for clinical assessment of the patient. Optimization of pump flow using LVAD parameters and echocardiographic and hemodynamics guidance are reviewed.
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