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Related Concept Videos

Types of Fever01:25

Types of Fever

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Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
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Patterns of Fever01:26

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Methods of reducing fever01:22

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The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
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Related Experiment Video

Updated: Feb 7, 2026

Cultivation Methods of Spirochetes from Borrelia burgdorferi Sensu Lato Complex and Relapsing Fever Borrelia
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Relapsing fever in a Moroccan man.

S Kahouli1, H Naoui2, J Uwingabiye1

  • 1Hôpital militaire d'instruction Mohamed V, Laboratoire de parasitologie, Faculté de médecine et de pharmacie, Université Mohammed V, Rabat, Maroc.

Medecine Et Sante Tropicales
|July 13, 2018
PubMed
Summary

Tick-borne relapsing fever, a Borrelia-caused zoonosis, is often misdiagnosed. Prompt diagnosis via spirochete identification in blood smears is crucial for effective antibiotic treatment.

Keywords:
BorreliosisMoroccotick-borne relapsing fever

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Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Parasitology

Background:

  • Tick-borne relapsing fever (TBRF) is a zoonotic disease caused by Borrelia spirochetes transmitted by ticks.
  • This life-threatening illness is frequently misdiagnosed due to non-specific symptoms.

Observation:

  • A 54-year-old man presented with isolated fever after hiking in Morocco.
  • Initial assessments revealed inflammatory syndrome and liver dysfunction, with negative blood cultures and serology for HIV and Lyme disease.
  • The patient experienced recurrent fever episodes, prompting malaria suspicion and subsequent blood smear analysis.

Findings:

  • Microscopic examination of May-Grünwald Giemsa stained blood smears revealed Borrelia spirochetes.
  • This confirmed the diagnosis of tick-borne relapsing fever.
  • The patient responded well to treatment withcycline drugs.

Implications:

  • TBRF should be considered in patients with intermittent fever and non-specific clinical or laboratory findings, especially with relevant epidemiological exposure.
  • Accurate diagnosis relies on identifying spirochetes in blood or cerebrospinal fluid smears.
  • Increased awareness and diagnostic vigilance are necessary for managing this underrecognized disease.