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Childhood Cancer in Basrah, Iraq During 2012-2016: Incidence and Mortality
Jasim N Al-Asadi1, Sarah J Ibrahim
1Department of Family and Community Medicine, College of Medicine, Basrah University, Basrah, Iraq.
Insights
Childhood cancer incidence in Basrah, Iraq, was 13.74 per 100,000, with leukemia being the most common type. Cancer distribution and rates align with those found in developing nations.
Area of Science:
- Pediatric Oncology
- Epidemiology
- Cancer Registry
Background:
- Childhood cancer incidence and type distribution vary globally.
- Understanding regional variations is crucial for public health.
- Data from Basrah, Iraq, was previously limited.
Purpose of the Study:
- To determine childhood cancer incidence and mortality rates in Basrah, Iraq, from 2012 to 2016.
- To analyze cancer types and their distribution in this pediatric population.
- To compare findings with international data.
Main Methods:
- A descriptive, registry-based study of children aged 0-14 years with newly diagnosed primary cancer.
- Cancer classification followed the International Classification of Childhood Cancer, Version 3 (ICCC-3).
- Incidence and mortality rates were calculated per 100,000 population, stratified by age and sex.
Main Results:
- 723 new childhood cancer cases were registered between 2012-2016 (male to female ratio 1.2:1).
- The overall incidence rate was 13.74/100,000, with an age-standardized rate (ASIR) of 13.87/100,000.
- Leukemia (35.4%), lymphoma (17.8%), and central nervous system tumors (11.9%) were the most common diagnoses. The overall cancer-specific mortality rate was 6.04/100,000 (ASMR 6.08/100,000).
Conclusions:
- Childhood cancer incidence in Basrah is comparable to rates in other developing countries.
- The observed cancer type distribution also aligns with patterns seen in developing regions.
- This study provides essential epidemiological data for Basrah, Iraq.
Abstract:
Background: Worldwide, childhood cancer is rare. In addition, a distinct variation in both incidence and type distribution was reported between countries. Aim: To estimate the incidence and mortality rates of childhood cancer in Basrah, Iraq during 2012-2016. Methods: This registry based descriptive study included children aged 0-14 years with primary cancer who were newly diagnosed in Basrah during 2012-2016. The types of malignant tumors were classified according to International Classification of Childhood Cancer, Version 3 (ICCC-3). The overall and specific incidence and mortality rates by age and sex were calculated per 100,000 population. Results: A total of 723 new cases of childhood cancer were registered during the five- year study period, with a male to-female ratio of 1.2/1. Children aged <4 years accounted for 43.1% of patients. The overall incidence rate was 13.74/100,000, and the age standardized incidence rate (ASIR) was 13.87/100,000. Boys showed higher incidence rate than girls (14.78 vs. 12.66/100,000). Leukemia was the most common type of childhood cancer accounting for 35.4%, followed by lymphoma (17.8%), and central nervous system tumors 11.9%. The overall cancer-specific mortality rate was 6.04/100,000 and the ASMR was 6.08/100,000 children. Conclusion: The incidence rate of childhood cancer in Basrah as well as the cancer type distribution was comparable to that reported for developing countries.
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