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[Two New Abietane Type Diterpenes from Pinecones of Pinus griffithii]
Objective:
To study the chemical constituents from the pinecones of Pinus griffithii.
Methods:
The constituents were separated and purified with chromatographic methods,and spectroscopic analysis were employed for structural elucidation.
Results:
Two new abietane type diterpenes and seven known compounds were isolated from the pinecones of Pinus griffithii,and were identified as 15-hydroxy-7α-methoxy-abiet-8,11,13-trien-18-oic acid( 1),7α,13-dihydroxy-podocarpane-8,11,13-trien-18-oic acid( 2),7,12,13,15-tetrahydroxy-abiet-8( 14)-en-18-oic acid( 3),7β,15-dihydroxy-abiet-8,11,13-trien-18-oic acid( 4),18-norabiet-8,11,13-trien-4,7,15-triol( 5),15-hydroxy-abiet-8,11,13-trien-18-oic acid( 6),7α-hydroxy-15-methoxy-abiet-8,11,13-trien-18-oic acid( 7),7α-hydroxypodocarpen-8( 14)-en-13-one-18-oic acid( 8), oleanolic acid( 9).
Conclusion:
Compounds 1,2 are the new abietane type diterpene,and all compounds are isolated from this plant for first time.
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