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Updated: Feb 5, 2026

Author Spotlight: Extended Oxygen Consumption Measurement in Retinal Pigment Epithelium Using Resipher
Published on: August 16, 2024
Long-Term In Vivo Oxygen Sensors for Peripheral Artery Disease Monitoring
Scott P Nichols1, Mary K Balaconis2, Rebecca M Gant2
1Profusa, Inc., College Station, TX, USA. scott.nichols@profusa.com.
Abstract:
Tracking of tissue oxygenation around chronic foot wounds may help direct therapy decisions in patients with peripheral artery disease (PAD). Novel sensing technology to enable such monitoring was tested over 9 months in a Sinclair mini-pig model. No adverse events were observed over the entire study period. Systemic and acute hypoxia challenges were detected during each measurement period by the microsensors. The median time to locate the sensor signal was 13 s. Lumee Oxygen microsensors appear safe for long-term repeated oxygen measurements over 9 months.
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