Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ions as Acids and Bases02:54

Ions as Acids and Bases

26.5K
Salts with Acidic Ions
Salts are ionic compounds composed of cations and anions, either of which may be capable of undergoing an acid or base ionization reaction with water. Aqueous salt solutions, therefore, may be acidic, basic, or neutral, depending on the relative acid-base strengths of the salt’s constituent ions. For example, dissolving the ammonium chloride in water results in its dissociation, as described by the equation:
26.5K
Indicators02:39

Indicators

61.0K
Certain organic substances change color in dilute solution when the hydronium ion concentration reaches a particular value. For example, phenolphthalein is a colorless substance in any aqueous solution with a hydronium ion concentration greater than 5.0 × 10−9 M (pH < 8.3). In more basic solutions where the hydronium ion concentration is less than 5.0 × 10−9 M (pH > 8.3), it is red or pink. Substances such as phenolphthalein, which can be used to determine the pH of a solution, are...
61.0K
Metal-Ligand Bonds02:51

Metal-Ligand Bonds

24.3K
The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
24.3K
Formation of Complex Ions03:45

Formation of Complex Ions

26.2K
A type of Lewis acid-base chemistry involves the formation of a complex ion (or a coordination complex) comprising a central atom, typically a transition metal cation, surrounded by ions or molecules called ligands. These ligands can be neutral molecules like H2O or NH3, or ions such as CN− or OH−. Often, the ligands act as Lewis bases, donating a pair of electrons to the central atom. These types of Lewis acid-base reactions are examples of a broad subdiscipline called coordination...
26.2K
Alkali Metals03:06

Alkali Metals

24.8K
Group 1 elements are soft and shiny metallic solids. They are malleable, ductile, and good conductors of heat and electricity. The melting points of the alkali metals are unusually low for metals and decrease going down the group, while the density increases going down the group with the exception of potassium (Table 1).
Table 1: Properties of the alkali metals
24.8K
Bonding in Metals02:32

Bonding in Metals

52.5K
Metallic bonds are formed between two metal atoms. A simplified model to describe metallic bonding has been developed by Paul Drüde called the “Electron Sea Model”. 
52.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A triboelectric radical generation route to chlorine disinfectants from brine.

Nature communications·2026
Same author

Hierarchical depth aware YOLO for efficient metal surface defect detection.

Scientific reports·2026
Same author

Twisted-Nematic Liquid Crystal-Infiltrated Bilayer Metasurface for Circular-Polarization LCoS Devices.

ACS applied optical materials·2026
Same author

Biosensors for Detecting Small Rho GTPases: Monitoring Expression and Activation.

BioEssays : news and reviews in molecular, cellular and developmental biology·2025
Same author

Electrically Tunable Geometric-Phase Optical Element with Hybrid Retardation and Subwavelength Pixel Size Enabled by Metasurface-Induced Liquid Crystal Patterning.

ACS applied optical materials·2025
Same author

Band Alignment and Interfacial Stability of Co<sub>3</sub>O<sub>4</sub> vs NiO as a Hole Transport Layer with FA<sub>0.4</sub>MA<sub>0.6</sub>PbI<sub>3</sub> Perovskite.

ACS applied materials & interfaces·2025

Related Experiment Video

Updated: Feb 5, 2026

Quantification of Heavy Metals and Other Inorganic Contaminants on the Productivity of Microalgae
10:20

Quantification of Heavy Metals and Other Inorganic Contaminants on the Productivity of Microalgae

Published on: July 10, 2015

16.5K

Triple-Indicator-Based Multidimensional Colorimetric Sensing Platform for Heavy Metal Ion Detections.

Noorhayati Idros1,2, Daping Chu1

  • 1Centre for Photonic Devices and Sensors, Department of Engineering , University of Cambridge , Cambridge CB3 0FA , United Kingdom.

ACS Sensors
|September 8, 2018
PubMed
Summary

This study introduces a low-cost paper-based microfluidic analytical device (μPAD) for detecting toxic heavy metals like mercury and lead in water. The portable device offers a simple, visual method for environmental and public health monitoring.

Keywords:
color calibrationheavy metalsmultidimensional sensingpaper-based microfluidicstriple indicator

More Related Videos

The Visual Colorimetric Detection of Multi-nucleotide Polymorphisms on a Pneumatic Droplet Manipulation Platform
10:01

The Visual Colorimetric Detection of Multi-nucleotide Polymorphisms on a Pneumatic Droplet Manipulation Platform

Published on: September 27, 2016

8.0K
Colorimetric Detection of Bacteria Using Litmus Test
10:05

Colorimetric Detection of Bacteria Using Litmus Test

Published on: September 17, 2016

9.9K

Related Experiment Videos

Last Updated: Feb 5, 2026

Quantification of Heavy Metals and Other Inorganic Contaminants on the Productivity of Microalgae
10:20

Quantification of Heavy Metals and Other Inorganic Contaminants on the Productivity of Microalgae

Published on: July 10, 2015

16.5K
The Visual Colorimetric Detection of Multi-nucleotide Polymorphisms on a Pneumatic Droplet Manipulation Platform
10:01

The Visual Colorimetric Detection of Multi-nucleotide Polymorphisms on a Pneumatic Droplet Manipulation Platform

Published on: September 27, 2016

8.0K
Colorimetric Detection of Bacteria Using Litmus Test
10:05

Colorimetric Detection of Bacteria Using Litmus Test

Published on: September 17, 2016

9.9K

Area of Science:

  • Environmental Science
  • Analytical Chemistry
  • Materials Science

Background:

  • Heavy metal pollution poses significant environmental and public health risks globally.
  • Current detection methods are costly, require specialized labs, and are time-consuming.
  • There is a need for accessible, portable, and rapid heavy metal detection techniques.

Purpose of the Study:

  • To develop a low-cost, paper-based microfluidic analytical device (μPAD) for monitoring multiple heavy metal ions.
  • To enable facile, portable, and disposable detection of toxic metals in environmental samples.
  • To provide a sensitive and accurate alternative to conventional laboratory-based methods.

Main Methods:

  • Utilized preloaded triple indicators or ligands on μPADs for colorimetric detection of metal ions.
  • Employed digital imaging and RGB color space analysis for quantitative color feature assessment.
  • Validated the device's performance using real water samples for simultaneous detection and discrimination.

Main Results:

  • The μPAD successfully detected and discriminated between various heavy metal ions (Hg, Pb, Cr, Ni, Cu, Fe) with high accuracy.
  • Colorimetric changes were observable by the naked eye and quantitatively analyzed.
  • Achieved sensitivity below safe limit concentrations with a controlled error range.

Conclusions:

  • The developed μPAD offers a promising, cost-effective solution for portable heavy metal monitoring.
  • This technology facilitates on-site, semiquantitative, and qualitative analysis of water quality.
  • The device has significant potential for widespread application in environmental surveillance and public health protection.