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Neuroanatomical Substrates for Risk Behavior.

Ifat Levy1

  • 11 Section of Comparative Medicine and Department of Neuroscience, Yale School of Medicine, New Haven, CT, USA.

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|September 14, 2018
PubMed
Summary
This summary is machine-generated.

Risk-taking varies greatly between individuals. Neuroimaging studies show brain networks, including the anterior insula and cingulate cortex, are involved in processing uncertainty, a key aspect of risk behavior.

Keywords:
ACCPPCambiguityfunctional MRIrisk takingstructural MRIuncertaintyventral striatum vmPFCvlPFCvmPFC

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Area of Science:

  • Neuroscience
  • Cognitive Neuroscience
  • Neuroimaging

Background:

  • Individual differences in risk-taking are significant.
  • Neuroimaging research has explored cognitive mechanisms underlying risk behavior.
  • Uncertainty processing is a key feature of risk-taking behavior.

Purpose of the Study:

  • To review functional and structural MRI studies on uncertainty processing and risk behavior.
  • To identify brain networks involved in processing uncertainty.
  • To explore how neural mechanisms relate to individual differences in risk tendencies.

Main Methods:

  • Review of functional and structural Magnetic Resonance Imaging (MRI) studies.
  • Analysis of studies using decision-making and learning paradigms.
  • Examination of neural correlates of uncertainty processing.

Main Results:

  • A network of brain areas, including posterior parietal cortex, anterior insula, anterior cingulate cortex, and ventrolateral prefrontal cortex, is implicated in uncertainty processing.
  • Individual differences in uncertainty processing are reflected in the function and structure of these brain areas.
  • These neural processes are integrated into value representations in ventromedial prefrontal cortex and ventral striatum.

Conclusions:

  • The identified brain network plays a crucial role in processing uncertainty during risk-taking.
  • Neural mechanisms underlying uncertainty processing contribute to individual differences in risk behavior.
  • Understanding these brain structures offers insights into the neural basis of risk tendencies.