Protein-Engineered Biomaterials for Cancer Theranostics.

Area of Science:

• Biomaterials Science
• Biomedical Engineering
• Protein Engineering

Background:

• Proteins are versatile biomaterials with applications in drug delivery, imaging, and therapy.
• Their biodegradability, biocompatibility, and inherent biological activities make them valuable for biomedical uses.
• Extensive research has focused on engineering proteins for specific biomedical applications over recent decades.

Purpose of the Study:

• To review strategies for engineering biomaterials for therapeutic protein delivery.
• To summarize recent developments in protein-based biomaterials for cancer theranostics.
• To provide an overview of the current landscape and future directions in protein biomaterials.

Main Methods:

• Literature review of protein biomaterial engineering strategies.
• Analysis of recent advancements in protein-based materials for cancer theranostics.
• Synthesis of information on therapeutic protein delivery systems.

Main Results:

• Various protein engineering strategies enable tailored biomaterial properties for drug delivery.
• Protein-based biomaterials show significant promise for integrated cancer diagnosis and therapy (theranostics).
• Numerous therapeutic proteins have successfully entered clinical applications.

Conclusions:

• Protein biomaterials offer a promising platform for advanced biomedical applications.
• Continued engineering efforts are crucial for optimizing protein-based systems for therapeutic delivery and cancer theranostics.
• The field is rapidly evolving with significant potential for clinical translation.