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The Meaning Response, "Placebo," and Methods.

Phil Hutchinson, Daniel E Moerman

    Perspectives in Biology and Medicine
    |October 9, 2018
    PubMed
    Summary
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    The "meaning response" explains placebo effects, suggesting people react to the significance of treatments, not the treatments themselves. This challenges conditioning and expectancy theories, proposing a new framework for understanding patient responses.

    Area of Science:

    • Medical Anthropology
    • Philosophy of Mind
    • Cognitive Science

    Background:

    • The placebo response has been explained by conditioning, response-expectancy, and the meaning response.
    • Dan Moerman (2002) argued the meaning response best explains placebo effects, proposing it replace "placebo effect/response."
    • Meaning responses are evident even without conditioning or expectation formation.

    Purpose of the Study:

    • To address criticisms of the meaning response theory.
    • To reconcile the meaning response with naturalistic and cognitive science perspectives.
    • To propose integrating ethnomethodological fieldwork into future research on meaning responses.

    Main Methods:

    • Literature review and theoretical analysis of existing explanations for placebo responses.

    Related Experiment Videos

  • Examination of criticisms regarding the meaning response and the naturalistic demand.
  • Proposal for incorporating ethnomethodological fieldwork.
  • Main Results:

    • The meaning response offers a comprehensive explanation for placebo effects, distinct from conditioning and expectancy.
    • Criticisms of the meaning response often stem from its perceived conflict with naturalistic philosophical and cognitive science paradigms.
    • Ethnomethodological fieldwork can provide empirical grounding for the meaning response theory.

    Conclusions:

    • The meaning response is a robust framework for understanding patient reactions to medical interventions.
    • Further research, particularly incorporating ethnomethodological approaches, is needed to fully validate and refine the meaning response theory.
    • Integrating qualitative, fieldwork-based methods can bridge the gap between the meaning response theory and naturalistic scientific inquiry.