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Updated: Feb 3, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Advanced Neuroimaging of Acute Ischemic Stroke: Penumbra and Collateral Assessment
Jeremy J Heit1, Greg Zaharchuk1, Max Wintermark1
1Department of Radiology, Division of Neuroimaging and Neurointervention, Stanford Healthcare, 300 Pasteur Drive, Stanford, CA 94305, USA.
Abstract:
Acute ischemic stroke (AIS) occurs when there is a sudden loss in cerebral blood flow due to embolic or thromboembolic occlusion of a cerebral or cervical artery. Patients with AIS require emergent neuroimaging to guide treatment, which includes intravenous thrombolysis and endovascular mechanical thrombectomy (EMT). Recent advances in AIS treatment by EMT has been driven in part by advances in computed tomography (CT) and MR imaging neuroimaging evaluation of ischemic penumbra and pial collateral vessels. The authors review advanced noninvasive brain imaging by CT and MR imaging for the evaluation of AIS focusing on penumbral and collateral imaging.
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