Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

453
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
453
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

411
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
411
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

399
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
399
Initiation of Translation02:33

Initiation of Translation

39.0K
Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are all required to assemble on the initiation codon of mRNA. This process consists of several steps that are mediated by different eIFs.
First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...
39.0K
Initiation of Translation02:33

Initiation of Translation

8.1K
8.1K
Kidney Structure01:45

Kidney Structure

75.3K
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
75.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Streamlining Informed Consent for Urinary Diversion Using an Artificial Intelligence-Generated Avatar System: A Novel Approach to Physician Work-Style Reform.

International journal of urology : official journal of the Japanese Urological Association·2026
Same author

Elucidating Characteristics of Co-Existent Overactive and Underactive Bladder in Participants of the 2023 Japan Community Health Survey (JaCS 2023) With Nocturia.

Neurourology and urodynamics·2026
Same author

Differences in Urodynamic Findings of Robot-Assisted Radical Prostatectomy Before and 2 Years After Surgery.

Neurourology and urodynamics·2026
Same author

Multi-Center, Real-World Registry Study of the UroLift Prostatic Urethral Lift (PUL) for Benign Prostatic Hyperplasia (BPH) in Japan.

International journal of urology : official journal of the Japanese Urological Association·2026
Same author

GWAS from a multicenter prospective study of radium-223 in bone-metastatic castration-resistant prostate cancer.

EJNMMI research·2026
Same author

Comparison of Urodynamic Outcomes of Surgery Using the Photoselective Vaporization 180 W XPS System and Transurethral Resection of the Prostate: A Propensity Score-Matched Analysis in Real-World Clinical Practice.

International journal of urology : official journal of the Japanese Urological Association·2026

Related Experiment Video

Updated: Feb 3, 2026

Robot-Assisted Kidney Transplantation
07:30

Robot-Assisted Kidney Transplantation

Published on: July 19, 2021

4.4K

[INITIAL EXPERIENCE OF DENOSUMAB TREATMENT FOR OSTEOPOROSIS AFTER KIDNEY TRANSPLANTATION].

Takeshi Maehana1, Toshiaki Tanaka1, Naoya Masumori1

  • 1Department of Urology, Sapporo Medical University School of Medicine.

Nihon Hinyokika Gakkai Zasshi. the Japanese Journal of Urology
|October 19, 2018
PubMed
Summary

Denosumab effectively treats osteoporosis in kidney transplant patients, improving bone mineral density and lowering bone turnover markers. This study found denosumab safe and effective for this patient group.

Keywords:
denosumabkidney transplantionosteoporosis

More Related Videos

Normothermic Machine Perfusion of Rat Kidneys for Transplantation
10:42

Normothermic Machine Perfusion of Rat Kidneys for Transplantation

Published on: January 27, 2026

7
Murine Kidney Transplant Technique
08:58

Murine Kidney Transplant Technique

Published on: October 20, 2015

17.3K

Related Experiment Videos

Last Updated: Feb 3, 2026

Robot-Assisted Kidney Transplantation
07:30

Robot-Assisted Kidney Transplantation

Published on: July 19, 2021

4.4K
Normothermic Machine Perfusion of Rat Kidneys for Transplantation
10:42

Normothermic Machine Perfusion of Rat Kidneys for Transplantation

Published on: January 27, 2026

7
Murine Kidney Transplant Technique
08:58

Murine Kidney Transplant Technique

Published on: October 20, 2015

17.3K

Area of Science:

  • Nephrology
  • Endocrinology
  • Orthopedics

Context:

  • Osteoporosis is a common complication after kidney transplantation.
  • The efficacy and safety of denosumab in this specific patient population are not well-established.
  • Bone health management is crucial for long-term graft survival and patient well-being.

Purpose:

  • To evaluate the efficacy and safety of denosumab for treating osteoporosis in patients who have undergone kidney transplantation.
  • To assess changes in bone mineral density (BMD) and bone turnover markers following denosumab treatment.
  • To monitor for adverse events and assess graft function during denosumab therapy.

Summary:

  • A retrospective review of four kidney transplant recipients with osteoporosis treated with denosumab was conducted.
  • After 12 months, significant increases in lumbar spine (5.5%) and femoral neck (3.0%) BMD were observed.
  • Bone turnover markers (TRACP-5b, P1NP) decreased markedly, and no significant adverse events or graft dysfunction were reported.

Impact:

  • Denosumab demonstrates potential as a safe and effective therapeutic option for osteoporosis management in kidney transplant recipients.
  • Findings suggest denosumab can improve bone density and reduce bone turnover without compromising graft function.
  • This study provides valuable preliminary evidence supporting the use of denosumab in a challenging clinical scenario.