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Updated: Feb 3, 2026

Large-Scale, Automated Production of Adipose-Derived Stem Cell Spheroids for 3D Bioprinting
Published on: March 31, 2022
3D Bioprinting of Adipose-Derived Stem Cells for Organ Manufacturing
Xiaohong Wang1,2, Chang Liu3
1Center of Organ Manufacturing, Department of Tissue Engineering, China Medical University (CMU), Shenyang, People's Republic of China. wangxiaohong709@163.com.
Abstract:
Organ manufacturing is an attractive high-tech research field which can solve the serious donor shortage problems for allograft organ transplantation, high throughput drug screening, and energy metabolism model establishment. How to integrate heterogeneous cell types along with other biomaterials to form bioartificial organs is one of the kernel issues for organ manufacturing. At present, three-dimensional (3D) bioprinting of adipose-derives stem cell (ADSC) containing hydrogels has shown the most bright futures with respect to overcoming all the difficult problems encountered by tissue engineers over the last several decades. In this chapter, we briefly introduce the 3D ADSC bioprinting technologies for organ manufacturing, especially for the branched vascular network construction.
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