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Updated: Feb 3, 2026

Production and Detection of Reactive Oxygen Species ROS in Cancers
Published on: November 21, 2011
Reactive Oxygen Species Responsive Naturally Occurring Phenolic-Based Polymeric Prodrug
S V Berwin Singh1,2, Angela Guma Adam3, Nirmalya Tripathy4
1Department of Physiology, Research Institute for Endocrine Sciences, Chonbuk National University Medical School, Jeonju, South Korea.
Abstract:
Reactive Oxygen Species (ROS) play a vital role in the biological system. Exaggerated, ROS have devastating effects on the human body leading to the pathophysiological condition including the transformation of a normal cell into a cancer phenotype. Nature has blessed us with various biomolecules that we use along with our dietary supplements. Using such therapeutic small molecules covalently incorporated into biodegradable polyoxalate polymer backbone with a responsive group forms an efficient drug delivery vehicle. This chapter "Reactive oxygen species responsive naturally occurring phenolic-based polymeric prodrug" will be focusing on redox-responsive polymers incorporated with naturally occurring phenolics and clinical application.
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