Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cranial and Spinal Meninges01:19

Cranial and Spinal Meninges

4.0K
The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
4.0K
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

3.2K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
3.2K
Chronic Pharyngitis01:23

Chronic Pharyngitis

11.9K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
11.9K
Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

570
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
570
Frustration and Conflict: Approach-Approach, Approach-Avoidance01:20

Frustration and Conflict: Approach-Approach, Approach-Avoidance

533
Frustration occurs when people are obstructed or prevented from achieving a desired goal or fulfilling a perceived need. For example, when someone's input is ignored in a discussion, it can lead to feelings of frustration. Conflict, however, arises from opposing interests, goals, or actions. Conflicts can take various forms based on the nature of these opposing desires or goals.
One common type of conflict is the Approach–Approach Conflict. In this case, a person faces two desirable...
533
Myasthenia Gravis: Diagnostic Tests01:15

Myasthenia Gravis: Diagnostic Tests

2.5K
Myasthenia gravis is an autoimmune condition affecting neuromuscular transmission, causing generalized weakness in skeletal muscles. Initial diagnoses rely on patients' signs, symptoms, and medical history. The challenge lies in distinguishing myasthenia from other muscular dystrophies. An important diagnostic feature is the significant improvement of symptoms after administering anticholinesterase inhibitors.
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
2.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Rare Case of I127V Heterozygous Transthyretin Amyloidosis With Atypical Transthoracic Echocardiogram Findings Presenting As Upper Extremity Sensorimotor Polyneuropathy.

Cureus·2022
Same author

Prion Disease.

Seminars in neurology·2019
Same author

Human Chronic Necrotizing Granulomatous Meningoencephalitis: A Novel Case Report.

Case reports in neurology·2018
Same author

Herpesvirus Infections of the Nervous System.

Continuum (Minneapolis, Minn.)·2018
Same author

Fatal Cerebral Edema, Seizures, and Hyponatremia After Trazodone Overdose.

Clinical neuropharmacology·2017
Same author

Chronic Autoimmune Meningoencephalitis and Periodic Fever Syndrome Treated with Anakinra.

Case reports in neurology·2017

Related Experiment Video

Updated: Feb 3, 2026

Combined Supine and Standing Imaging for Varicocele: An Improved Diagnostic Approach
04:15

Combined Supine and Standing Imaging for Varicocele: An Improved Diagnostic Approach

Published on: November 22, 2024

720

Diagnostic Approach to Chronic Meningitis.

Kelly J Baldwin1, Jose David Avila1

  • 1Department of Neurology, Geisinger Commonwealth School of Medicine, Geisinger Medical Center, 100 North Academy Avenue, Danville, PA 17822, USA.

Neurologic Clinics
|October 28, 2018
PubMed
Summary
This summary is machine-generated.

Chronic meningitis, a persistent cerebrospinal fluid inflammation, presents a diagnostic challenge. This article outlines a systematic approach for diagnosing chronic meningitis, covering infectious, autoimmune, and neoplastic causes.

Keywords:
Chronic meningitisCryptococcusFungal meningitisLeptomeningeal carcinomatosisNeuroborreliosisNeurosarcoidosisSyphilisTuberculosis

More Related Videos

Isolating Central Nervous System Tissues and Associated Meninges for the Downstream Analysis of Immune cells
09:35

Isolating Central Nervous System Tissues and Associated Meninges for the Downstream Analysis of Immune cells

Published on: May 19, 2020

10.9K
Machine Learning-Based Cough Tone Classification: Diagnostic Exploration of Chronic Obstructive Pulmonary Disease and Respiratory Tract Infections
06:22

Machine Learning-Based Cough Tone Classification: Diagnostic Exploration of Chronic Obstructive Pulmonary Disease and Respiratory Tract Infections

Published on: September 19, 2025

497

Related Experiment Videos

Last Updated: Feb 3, 2026

Combined Supine and Standing Imaging for Varicocele: An Improved Diagnostic Approach
04:15

Combined Supine and Standing Imaging for Varicocele: An Improved Diagnostic Approach

Published on: November 22, 2024

720
Isolating Central Nervous System Tissues and Associated Meninges for the Downstream Analysis of Immune cells
09:35

Isolating Central Nervous System Tissues and Associated Meninges for the Downstream Analysis of Immune cells

Published on: May 19, 2020

10.9K
Machine Learning-Based Cough Tone Classification: Diagnostic Exploration of Chronic Obstructive Pulmonary Disease and Respiratory Tract Infections
06:22

Machine Learning-Based Cough Tone Classification: Diagnostic Exploration of Chronic Obstructive Pulmonary Disease and Respiratory Tract Infections

Published on: September 19, 2025

497

Area of Science:

  • Neurology
  • Infectious Diseases
  • Immunology

Background:

  • Chronic meningitis is defined by cerebrospinal fluid (CSF) pleocytosis lasting over 4 weeks.
  • The differential diagnosis is broad, including infectious, autoimmune, neoplastic, and idiopathic causes.
  • A significant proportion of cases remain undiagnosed, posing a clinical challenge.

Purpose of the Study:

  • To propose a structured diagnostic approach for chronic meningitis.
  • To aid clinicians in identifying the underlying cause of persistent meningitis.
  • To review common etiologies and treatment strategies.

Main Methods:

  • The study suggests a diagnostic algorithm integrating clinical history, physical examination, targeted laboratory tests, and neuroimaging.
  • Case presentations illustrate the application of this diagnostic strategy.
  • A review of common infectious, autoimmune, and neoplastic causes is included.

Main Results:

  • The proposed approach aims to systematically narrow down the differential diagnosis.
  • Case examples highlight the utility of the diagnostic algorithm.
  • Key findings from common etiologies and their treatments are discussed.

Conclusions:

  • A systematic diagnostic approach is crucial for managing chronic meningitis effectively.
  • Integrating clinical data with advanced testing and imaging aids in identifying the cause.
  • Understanding common etiologies guides appropriate therapeutic interventions.