Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Menopause

Menopause

Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Per- and polyfluoroalkyl substances, vitamin D, and risk of preterm birth in a Canadian cohort.

Environmental research·2026

Same author

Criteria to Assess Health Equity Implications of Research Articles in a Family Medicine Residency Journal Club.

WMJ : official publication of the State Medical Society of Wisconsin·2026

Same author

Practical Tips for Addressing Patient Loneliness in Primary Care.

Family practice management·2026

Same author

Completing a Scoping Review.

Family medicine·2026

Same author

Framing Primary Care Clinicians' Experiences Managing Behavioral and Psychological Symptoms of Dementia: Insights From an Educational Intervention.

WMJ : official publication of the State Medical Society of Wisconsin·2026

Same author

Loneliness and Leadership.

Family medicine·2026

Same journal

Primary Care at the Center of America's Mental Health Landscape.

Primary care·2026

Same journal

We Care, and We Will Listen.

Primary care·2026

Same journal

Addressing Sexual Health in Primary Care.

Primary care·2026

Same journal

Diagnosis and Management of Eating Disorders in Adolescents and Young Adults.

Primary care·2026

Same journal

Management of Concomitant Mental Health Conditions in Older Adults with Cognitive Impairment.

Primary care·2026

Same journal

Nonpharmacologic Management of Insomnia Disorder in Primary Care.

Primary care·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Feb 3, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause

Published on: August 13, 2019

Menopause.

Beth Potter¹, Sarina Schrager¹, Jessica Dalby¹

¹Department of Family Medicine and Community Health, University of Wisconsin School of Medicine and Public Health, 1100 Delaplaine, Madison, WI 53715, USA.

|November 8, 2018

Summary

This summary is machine-generated.

The menopausal transition involves physical and psychological changes, including irregular periods and symptoms like hot flashes. Understanding normal changes versus potential issues is key for managing women's health during this phase.

Keywords:

Genitourinary symptoms of menopause Hormone replacement therapy (HRT)Menopause Perimenopause Vasomotor symptoms

More Related Videos

A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice

A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice

Published on: April 7, 2014

Author Spotlight: Investigating the Relationship Between FSH and Pathophysiological Changes in Perimenopausal Women - Insights from a Mouse Model

Author Spotlight: Investigating the Relationship Between FSH and Pathophysiological Changes in Perimenopausal Women - Insights from a Mouse Model

Published on: August 11, 2023

Related Experiment Videos

Last Updated: Feb 3, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause

Published on: August 13, 2019

A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice

A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice

Published on: April 7, 2014

Author Spotlight: Investigating the Relationship Between FSH and Pathophysiological Changes in Perimenopausal Women - Insights from a Mouse Model

Author Spotlight: Investigating the Relationship Between FSH and Pathophysiological Changes in Perimenopausal Women - Insights from a Mouse Model

Published on: August 11, 2023

Area of Science:

Reproductive endocrinology and women's health.

Background:

The menopausal transition is characterized by significant physiological and psychological shifts.
Common symptoms include irregular menses, vasomotor disturbances, sleep disturbances, mood alterations, and genitourinary changes.

Purpose of the Study:

To delineate normal physiological changes during the menopausal transition.
To identify and evaluate potentially pathological changes.
To discuss management options for quality of life impacting menopausal symptoms.

Main Methods:

Review of current literature on menopausal physiology and symptomology.
Clinical guidelines for evaluating menopausal symptoms.
Overview of available therapeutic interventions.

Main Results:

Menopausal transition presents a spectrum of symptoms impacting women's well-being.
Distinguishing physiological from pathological changes requires careful clinical assessment.
Fertility can persist despite irregular cycles.

Conclusions:

Comprehensive understanding of menopausal changes is crucial for accurate diagnosis and management.
Timely intervention can significantly improve quality of life for women experiencing bothersome menopausal symptoms.