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Biotribological Testing and Analysis of Articular Cartilage Sliding against Metal for Implants
Published on: May 14, 2020
Orthobiologics for Focal Articular Cartilage Defects
Taylor M Southworth1, Neal B Naveen1, Benedict U Nwachukwu1
1Department of Orthopedics, Rush University Medical Center, 1611 West Harrison, Suite 300, Chicago, IL 60612, USA.
Abstract:
Focal chondral defects of the knee are extremely common and often result in pain, dysfunction, joint deterioration, and, ultimately, the development of osteoarthritis. Due to the limitations of conventional treatments for focal chondral defects of the knee, orthobiologics have recently become an area of interest. Orthobiologics used for cartilage defects include (but are not limited to) bone marrow aspirate concentrate, adipose-derived mesenchymal stem cells, platelet-rich plasma, and micronized allogeneic cartilage. Each of these products can be applied in the clinical setting, as an isolated surgical procedure, or as an augment to cartilage restoration surgery.
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