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Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection
Published on: February 1, 2022
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Graphene-Based Nanomaterials and Their Applications in Biosensors
Young Jun Kim1, Bongjin Jeong2
1BioMedicalIT Department, Electronics and Telecommunications Research Institute (ETRI), Daejeon, South Korea. junkim@etri.re.kr.
Advances in Experimental Medicine and Biology
|November 25, 2018
Summary
Graphene derivatives like graphene oxides (GOs) and graphene quantum dots (GQDs) are advancing biosensor technology. These nanomaterials offer unique optoelectronic properties for electrochemical and fluorescence-based detection schemes in biological applications.
Area of Science:
- Materials Science
- Nanotechnology
- Biotechnology
Background:
- Graphene and its derivatives, including graphene oxides (GOs) and graphene quantum dots (GQDs), are attracting significant research interest.
- These materials exhibit unique optoelectronic properties, making them promising for various applications in biology, IT, and energy.
Purpose of the Study:
- To describe the preparation and functionalization of graphene and GOQ derivatives.
- To highlight recent advancements in graphene and GQD-based biosensors.
- To focus on immunoassay and oligonucleotide assay applications using these nanomaterials.
Main Methods:
- Preparation and functionalization techniques for graphene and GOQ derivatives.
- Characterization of their optoelectronic properties.
- Development of electrochemical and fluorescence-based detection schemes for biosensing.
Main Results:
- Graphene derivatives show significant potential for biosensing applications.
- Immunoassays and oligonucleotide assays are effectively implemented using graphene-based platforms.
- Electrochemical and fluorescence detection methods are optimized for high sensitivity.
Conclusions:
- Graphene and its derivatives are highly promising for advanced biosensor development.
- The unique properties of GOs and GQDs enable sensitive and specific biological detection.
- Future research will likely focus on refining these biosensor systems for diverse biological and medical diagnostics.
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