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Updated: Feb 1, 2026
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Synthesis and Characterization of Supramolecular Colloids
Published on: April 22, 2016
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Conjunctival Colloid Milium.
Mona Bhargava1, Saket Benurwar2, S Krishnakumar3
1Department of Cornea and Refractive Surgery, Sankara Nethralaya, Kolkata, India.
Cornea
|December 1, 2018
Summary
This case report details a rare instance of conjunctival colloid milium in an adult, emphasizing its distinction from more serious conditions through histopathology.
Area of Science:
- Ophthalmology
- Dermatology
- Pathology
Background:
- Colloid milium is a rare deposition disease affecting the skin.
- Conjunctival involvement is exceptionally uncommon.
Observation:
- A 45-year-old woman presented with a slow-growing, painless mass in the medial canthal region extending to the inferior fornix and bulbar conjunctiva.
- The lesion was associated with redness and underwent excisional biopsy with amniotic membrane transplantation.
Findings:
- Histopathology revealed homogenous amorphous eosinophilic material consistent with nodular colloid milium.
- Key diagnostic exclusions included solar damage, amyloidosis (negative Congo red stain), lipoid proteinosis, plasmacytoma, and conjunctival lymphoma.
Implications:
- This case highlights the importance of accurate histopathological diagnosis for conjunctival colloid milium.
- Distinguishing this rare condition from other periocular masses with similar clinical appearances is crucial for appropriate management and prognosis.
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