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Effectiveness of S-PRG Filler-Containing Toothpaste in Inhibiting Demineralization of Human Tooth Surface
Bennett T Amaechi1, Hariyali Kasundra1, Deepika Joshi1
1Department of Comprehensive Dentistry, University of Texas Health Science Center, San Antonio, Texas, USA.
The Open Dentistry Journal
|December 4, 2018
Summary
Surface Pre-reacted Glass-ionomer (S-PRG) filler toothpastes significantly prevent tooth demineralization. S-PRG dentifrices show greater effectiveness than sodium fluoride in caries control.
Area of Science:
- Dental Research
- Cariology
- Materials Science
Background:
- Dental caries remains a significant public health concern.
- Developing effective preventive strategies is crucial for oral health.
- Surface Pre-reacted Glass-ionomer (S-PRG) filler is a novel material for dental applications.
Purpose of the Study:
- To evaluate the efficacy of toothpastes containing S-PRG filler in preventing tooth demineralization.
- To compare the anti-demineralization effects of S-PRG toothpastes with sodium fluoride (NaF) toothpaste and a control.
- To assess the dose-dependent effect of S-PRG filler concentration on caries prevention.
Main Methods:
- A pH-cycling caries model was employed using 210 tooth blocks.
- Tooth blocks were divided into seven groups, including control, NaF, and varying concentrations of S-PRG (1%, 5%, 20%, 30%).
- Demineralization was quantified using Quantitative Light-induced Fluorescence (QLF) and Transverse Microradiography (TMR).
Main Results:
- All S-PRG containing toothpastes significantly inhibited demineralization compared to the control group.
- Higher concentrations of S-PRG showed greater reductions in demineralization (up to 69.8%).
- NaF toothpaste and 0% S-PRG showed minimal or no significant reduction in demineralization compared to the control.
Conclusions:
- Toothpastes with S-PRG filler are effective in preventing tooth demineralization.
- S-PRG filler-containing dentifrices demonstrate superior anti-demineralization efficacy compared to 1100 ppm sodium fluoride.
- S-PRG technology presents a promising approach for caries management.
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