Related Experiment Videos
[Single day treatment in acute cystitis]
1Department of Urology, Noto General Hospital.
Hinyokika Kiyo. Acta Urologica Japonica
|May 1, 1988
Summary
Norfloxacin, ofloxacin, and trimethoprim-sulfamethoxazole effectively treated acute cystitis in most patients. However, effectiveness varied by bacterial cause, with E. coli infections responding better than S. epidermidis.
Area of Science:
- Urology
- Infectious Diseases
- Pharmacology
Context:
- Acute cystitis is a common urinary tract infection.
- Antibiotic resistance is a growing concern in treating UTIs.
Purpose:
- To evaluate the clinical efficacy and recurrence rates of single-day treatments for acute cystitis.
- To compare the effectiveness of norfloxacin, ofloxacin, and trimethoprim-sulfamethoxazole.
Summary:
- A study of 114 patients with acute cystitis found high overall clinical efficacy (89% excellent) with single-day treatments of norfloxacin, ofloxacin, or trimethoprim-sulfamethoxazole.
- Recurrence was observed in 8% of patients within 6 weeks.
- Treatment effectiveness and recurrence rates were less favorable for infections caused by Staphylococcus epidermidis compared to Escherichia coli.
Impact:
- Provides evidence for the efficacy of short-course antibiotic therapy in acute cystitis.
- Highlights the importance of considering causative pathogens, such as E. coli and S. epidermidis, when selecting antibiotics.
- Informs clinical decision-making for managing acute uncomplicated cystitis.