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Related Experiment Video

Updated: Feb 1, 2026

Management of Respiratory Motion Artefacts in 18F-fluorodeoxyglucose Positron Emission Tomography using an Amplitude-Based Optimal Respiratory Gating Algorithm

Management of Respiratory Motion Artefacts in 18F-fluorodeoxyglucose Positron Emission Tomography using an Amplitude-Based Optimal Respiratory Gating Algorithm

Published on: July 23, 2020

Optimizing respiratory management in resource-limited settings.

Rebecca Inglis^1,2, Emmanuel Ayebale^3,4, Marcus J Schultz^5,6,7

¹Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Mahosot Hospital, Vientiane, Lao People's Democratic Republic.

Current Opinion in Critical Care

|December 12, 2018

Summary

This summary is machine-generated.

Management of acute respiratory failure in low- and middle-income countries (LMICs) should prioritize avoiding invasive mechanical ventilation. Noninvasive methods like bubble continuous positive airway pressure show promise in reducing mortality in resource-limited settings.

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Area of Science:

Critical Care Medicine
Global Health
Respiratory Medicine

Background:

Acute respiratory failure presents significant challenges in low- and middle-income countries (LMICs).
Mechanical ventilation in LMICs is associated with high mortality rates (36-72%) and iatrogenic complications.
Resource limitations in LMICs necessitate context-specific management strategies.

Purpose of the Study:

To review and abstract management principles for acute respiratory failure in resource-limited settings.
To identify strategies relevant to low- and middle-income countries (LMICs).
To guide clinical practice in managing acute respiratory failure with limited resources.

Main Methods:

Literature review focusing on acute respiratory failure management in LMICs.
Synthesis of evidence on noninvasive and invasive ventilation strategies.
Analysis of mortality data and iatrogenic complications.

Main Results:

Noninvasive ventilation, including bubble continuous positive airway pressure, demonstrates effectiveness in reducing mortality in pediatric acute respiratory failure.
Trials indicate that noninvasive ventilation can be safely implemented in resource-low settings.
Avoiding intubation and expediting weaning are crucial for improving outcomes.

Conclusions:

Management should focus on avoiding intubation whenever feasible.
Improving the safety and efficiency of mechanical ventilation, including timely weaning, is essential.
Development of robust, context-appropriate respiratory support technologies is a key future direction.