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Early Hemodynamic Performance of the Crown PRT Aortic Prosthesis: A Prospective Study
Simon M Duggan1, Syed Sadeque2, Danai Karamanou2
1Wessex Cardiothoracic Centre, Southampton General Hospital, Tremona Road, Southampton, UK. Electronic correspondence: drsimonduggan@gmail.com.
The Journal of Heart Valve Disease
|December 19, 2018
Summary
The Crown PRT aortic prosthesis shows effective hemodynamic performance and clinical outcomes up to one year post-implantation. This bioprosthesis offers satisfactory results with low complication rates, comparable to other devices.
Area of Science:
- Cardiology
- Biomedical Engineering
- Surgical Innovation
Background:
- Limited data exists on the hemodynamic progression and clinical outcomes of the Crown PRT aortic prosthesis.
- This study evaluates the latest Crown PRT bioprosthesis in a cohort of patients.
Purpose of the Study:
- To report clinical and hemodynamic outcomes after Crown PRT aortic prosthesis implantation.
- To assess the efficacy and safety of the Crown PRT bioprosthesis over a one-year follow-up period.
Main Methods:
- Prospective data collection from 55 patients undergoing aortic valve replacement (AVR) with the Crown PRT bioprosthesis.
- Evaluation of clinical, echocardiographic, and functional capacity data, including transprosthetic gradients, Doppler velocity index (DVI), and effective orifice area index (EOAi).
Main Results:
- No in-hospital deaths; low rates of stroke (3.6%) and permanent pacemaker insertion (1.8%).
- Stable hemodynamic parameters (gradients, DVI, EOAi) observed at one-year follow-up, comparable to pre-discharge values.
- Significant improvement in patient functional status (95% NYHA class I or II) and a 36% decrease in left ventricular mass.
Conclusions:
- The Crown PRT bioprosthesis is effective, demonstrating satisfactory hemodynamics and freedom from reoperation.
- It exhibits a low incidence of valve-related complications, comparable to contemporary bioprostheses.
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