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Updated: Jan 30, 2026

Purification and Aggregation of the Amyloid Precursor Protein Intracellular Domain
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Soluble Amyloid Precursor Protein α: Friend or Foe?

Nicola J Corbett1, Nigel M Hooper2

  • 1Division of Neuroscience & Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.

Advances in Experimental Medicine and Biology
|January 15, 2019
PubMed
Abstract

Keywords:
A disintegrin and metalloproteinase domain-containing protein 10 (ADAM10)AgeingAmyloid precursor protein (APP)Dendritic spinesDevelopmentNeurodegenerationNeuroprotectionSoluble amyloid precursor protein α (sAPPα)Synaptic plasticity

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