Related Experiment Video
Updated: Jan 30, 2026

Author Spotlight: A Stable Phantom Material for Optical and Acoustic Imaging
Published on: June 16, 2023
Proposed changes to the ACR phantom filling procedure for more accurate and consistent activity concentrations
1Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Objectives:
The phantom filling procedures currently specified by the American College of Radiology (ACR) for its PET accreditation program unnecessarily limit how tight the tolerances can be made on the accuracy requirements for the concentrations measured in the resultant images.
Methods:
New procedures are proposed to improve the accuracy and consistency of the concentrations within the phantom at the time of imaging. These improvements are gained by exchanging the difficult process of accurately measuring a dose with the more easily achieved accurate measurements of time and liquid volume to control final radioactivity concentrations. A comparison of the results when following the two filling procedures is made.
Results:
The variability in metrics specified by the ACR was approximately halved by following the new procedures.
Conclusion:
These improvements allow tighter thresholds to be applied when evaluating image quality and quantitative accuracy of the PET images. These changes also render this phantom data more suitable for inter-PET-scanner harmonization and improve its utility for comparing image reconstruction methods.
Related Concept Videos
Concentration Cells
Consider the following voltaic cell:
Solution Concentration and Dilution
Stress Concentrations
The stress...
Stress Concentrations
Concentration and Rate Law
For example, in a generic reaction aA + bB ⟶ products, where a and b are stoichiometric coefficients, the rate law can be written as:
Calculating Equilibrium Concentrations
A more...

