Trophoblastic disease: clinical pathology of hydatidiform moles

Hydatidiform moles are divided into two syndromes: those of complete and partial moles. Both forms are genetically, morphologically, and clinically distinct. Choriocarcinoma can be associated with the complete mole that has not been described for the partial syndrome. Residual trophoblastic disease, on the contrary, can be found with either syndrome, the substrate being locally invasive (nonembolic) behaviour.