Related Experiment Video
Updated: Jan 30, 2026

Characterization of the Effects of Migrastatic Inhibitors on 3D Tumor Spheroid Invasion by High-resolution Confocal Microscopy
Published on: September 16, 2019
[NON-CARDIAL EFFECTS OF SGLT2 INHIBITORS (REVIEW)]
I Doroshkevych1, L Vozniuk1, N Voloshchuk1
1Vinnytsia National Pirogov Memorial Medical University, Ukraine.
Abstract:
The article reveals the efficacy and safety aspects of a new class of antidiabetic drugs - SGLT2 inhibitors. The results of clinical and experimental studies of the principle of renal glucose reabsorption inhibition usage in the treatment of type 2 diabetes are presented in the article. Drugs of this class offer a new, non-insulin-dependent mechanism of action, lack of negative effect on body weight, favorable pharmacokinetic properties and good tolerance. However, data, requiring further more detailed analysis, were found, namely: a glucosuria as a risk factor for genitourinary system infections, increased levels of blood creatinine, increased urinary calcium excretion, ketogenesis. Also nephrogenic and cancer effects need more detailed analysis according to the ratio of risk/benefit.
More Related Videos
Related Concept Videos
Review and Preview
Percentiles are a type of fractile that partition data into...
Review and Preview
Eukaryotic Transcription Inhibitors
Eukaryotic transcription inhibitors usually contain two distinct domains, a...
Buffer Effectiveness
The buffer capacity is the amount of acid or base that can be added to a given volume...
Framing Effects
Dipeptidyl Peptidase 4 Inhibitors

