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Related Concept Videos

Compact Bone01:27

Compact Bone

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Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
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Compacting Factor test01:22

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The compacting factor test is a method used to assess the workability of concrete. It is  especially suitable for concrete mixes containing aggregates up to one and a half inches in size. This test involves specialized equipment consisting of two truncated cone-shaped hoppers and a cylinder, all with polished interior surfaces to minimize friction.
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Long Division of Polynomials01:26

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Polynomial division is an essential algebraic process to simplify expressions and solve equations. Just as numerical division separates a number into quotient and remainder, polynomial long division partitions a polynomial into simpler components; in this context, the dividend is the polynomial being divided, the divisor is the expression dividing it, and the result is expressed in terms of a quotient and a remainder.The division begins by arranging the dividend and divisor in standard...
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Frequency-dependent Selection01:21

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When the fitness of a trait is influenced by how common it is (i.e., its frequency) relative to different traits within a population, this is referred to as frequency-dependent selection. Frequency-dependent selection may occur between species or within a single species. This type of selection can either be positive—with more common phenotypes having higher fitness—or negative, with rarer phenotypes conferring increased fitness.
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Related Experiment Video

Updated: Jan 30, 2026

Digital Inline Holographic Microscopy DIHM of Weakly-scattering Subjects
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Digital Inline Holographic Microscopy DIHM of Weakly-scattering Subjects

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Simple, stable, compact implementation of frequency-division-multiplexed microscopy by inline interferometry.

Hiroshi Kanno, Hideharu Mikami, Yasin Kaya

    Optics Letters
    |February 1, 2019
    PubMed
    Summary
    This summary is machine-generated.

    Frequency-division-multiplexed (FDM) imaging achieves high-speed imaging using inline interferometry, overcoming limitations of conventional methods. This simplified approach enables rapid 2D imaging of biological samples at 15,300 frames per second.

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    Area of Science:

    • Optics and Photonics
    • Biomedical Imaging
    • Cell Biology

    Background:

    • Conventional imaging is limited by sensor frame rates, hindering high-speed applications.
    • Frequency-division-multiplexed (FDM) imaging offers a solution but is often complex and unstable due to Mach-Zehnder interferometer implementations.

    Purpose of the Study:

    • To develop a simple, stable, and compact implementation of FDM imaging.
    • To demonstrate the practical applicability of the enhanced FDM imaging technique.

    Main Methods:

    • Implemented FDM imaging using inline interferometry, replacing complex Mach-Zehnder setups.
    • Acquired 2D bright-field and fluorescence images of various samples.

    Main Results:

    • Achieved high-speed 2D imaging within 65.5 microseconds per frame.
    • Demonstrated image acquisition at a rate of 15,300 frames per second.
    • Successfully imaged fluorescent beads, microalgal cells, and breast cancer cells.

    Conclusions:

    • The inline interferometry-based FDM imaging is a simple, stable, and compact alternative for high-speed imaging.
    • This technique significantly enhances the accessibility and practicality of FDM imaging for biological and medical applications.