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Updated: Jan 29, 2026

Author Spotlight: Advancing Structural and Biochemical Studies of Proteins Through Thermal Shift Assays
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Author Spotlight: Advancing Structural and Biochemical Studies of Proteins Through Thermal Shift Assays

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TSA-CRAFT: A Free Software for Automatic and Robust Thermal Shift Assay Data Analysis

Po-Hsien Lee1, Xi Xiao Huang1, Bin Tean Teh1,2,3,4

  • 11 Cancer Science Institute of Singapore, National University of Singapore, Singapore.

SLAS Discovery : Advancing Life Sciences R & D
|February 13, 2019
PubMed
Summary

A new software, Thermal Shift Assay-Curve Rapid and Automatic Fitting Tool (TSA-CRAFT), automates thermal shift assay (TSA) data analysis. This tool provides accurate results for drug discovery and structural biology applications.

Keywords:
automatic Tm analysisdifferential scanning fluorimetryhigh-throughput ligand screeningthermal shift assaythermofluor

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