Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Vaccinations01:51

Vaccinations

51.5K
Overview
51.5K
Global Climate Change01:50

Global Climate Change

28.9K
Throughout its ~4.5 billion year history, the Earth has experienced periods of warming and cooling. However, the current drastic increase in global temperatures is well outside of the Earth’s cyclic norms, and evidence for human-caused global climate change is compelling. Paleoclimatology, the study of ancient climate conditions, provides ample evidence for human-caused global climate change by comparing recent conditions with those in the past.
28.9K
Cancer Vaccines01:30

Cancer Vaccines

1.0K
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
1.0K
Introduction to Global Positioning System01:30

Introduction to Global Positioning System

505
The Global Positioning System (GPS) revolutionized positioning on Earth, providing precise location data through satellite ranging. The GPS system was developed in 1978 by the U.S. Department of Defense  for military use, and it became available for civilian applications in 1983, transforming fields including navigation, fleet management, and time synchronization for telecommunications systems.GPS consists of satellites in medium Earth orbit, about 20,200 kilometers above the surface,...
505
Errors in Global Positioning System01:26

Errors in Global Positioning System

348
Global Positioning System (GPS) technology has revolutionized navigation and positioning, but its accuracy is often compromised by various errors. These errors, stemming from environmental, satellite, and receiver-related factors, require careful mitigation to ensure reliable performance across applications.Atmospheric ErrorsGPS signals travel through the Earth’s ionosphere and troposphere, introducing delays which affect accuracy. The ionosphere is strongly influenced by charged particles,...
348
Global Regulatory Systems01:28

Global Regulatory Systems

660
Global regulatory systems in bacteria enable rapid and coordinated responses to environmental changes by integrating sensory inputs with gene expression, ensuring efficient adaptation to fluctuating conditions. Key global regulatory mechanisms include regulons, two-component systems, sigma factors, and secondary messengers.Regulons and Global RegulatorsA regulon is a collection of genes and operons controlled by a common global regulator. These regulators enable bacteria to prioritize resource...
660

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Country-level perspectives and priorities to guide the development of Invasive non-Typhoidal Salmonella (iNTS) vaccines: Insights from seven countries.

PLoS neglected tropical diseases·2026
Same author

Dengue Vaccine Development and Deployment into Routine Immunization.

Vaccines·2025
Same author

What is the current evidence base for measles vaccination earlier than 9 months of age?: Report from an informal technical consultation of the World Health Organization.

Vaccine·2025
Same author

Clinical and regulatory development strategies for GBS vaccines intended for maternal immunisation in low- and middle-income countries.

Vaccine·2025
Same author

Global Status of Adult Immunization Post COVID-19 Pandemic.

Vaccines·2025
Same author

Consultation report - considerations for a regulatory pathway for bivalent Salmonella Typhi/Paratyphi A vaccines for use in endemic countries.

Vaccine·2025
Same journal

Antibiotic Treatment Duration for Uncomplicated Monomicrobial Enterococcal Bloodstream Infection: A Multicenter Target Trial Emulation.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Larger Blood Volume Increases Detection of Fastidious Mycobacteria and Fungi in Blood Culture.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Anticalcitonin: Limited utility of a context-dependent biomarker demonstrated in another real-world data set.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Procalcitonin Testing in Community-Acquired Pneumonia.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Wanted: A Relevant Correlate of Protection for Dengue Vaccines.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Safety and Immunogenicity of the Live-Attenuated Quadrivalent Dengue Vaccine V181 Compared With Butantan-DV Among Healthy Adults in Brazil: A Randomized, Double-Blind, Phase 2 Trial.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
See all related articles

Related Experiment Video

Updated: Jan 29, 2026

Expression and Purification of Virus-like Particles for Vaccination
06:17

Expression and Purification of Virus-like Particles for Vaccination

Published on: June 2, 2016

22.8K

Revised Global Typhoid Vaccination Policy.

Adwoa D Bentsi-Enchill1, Joachim Hombach1

  • 1Department of Immunization, Vaccines and Biologicals, World Health Organization, Geneva, Switzerland.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|February 16, 2019
PubMed
Summary
This summary is machine-generated.

Typhoid conjugate vaccines (TCVs) are now recommended for routine immunization to combat typhoid fever, a significant global health issue. This policy shift enables vaccination as a realistic control strategy, especially when combined with improved sanitation and surveillance.

Keywords:
WHO vaccine position paperimmunization policytyphoid conjugate vaccinestyphoid fevervaccination strategies

More Related Videos

Intralymphatic Immunotherapy and Vaccination in Mice
07:33

Intralymphatic Immunotherapy and Vaccination in Mice

Published on: February 2, 2014

24.0K
The Use of Mixed Reality in Custom-Made Revision Hip Arthroplasty: A First Case Report
07:45

The Use of Mixed Reality in Custom-Made Revision Hip Arthroplasty: A First Case Report

Published on: August 4, 2022

3.8K

Related Experiment Videos

Last Updated: Jan 29, 2026

Expression and Purification of Virus-like Particles for Vaccination
06:17

Expression and Purification of Virus-like Particles for Vaccination

Published on: June 2, 2016

22.8K
Intralymphatic Immunotherapy and Vaccination in Mice
07:33

Intralymphatic Immunotherapy and Vaccination in Mice

Published on: February 2, 2014

24.0K
The Use of Mixed Reality in Custom-Made Revision Hip Arthroplasty: A First Case Report
07:45

The Use of Mixed Reality in Custom-Made Revision Hip Arthroplasty: A First Case Report

Published on: August 4, 2022

3.8K

Area of Science:

  • Public Health
  • Vaccinology
  • Infectious Diseases

Background:

  • Typhoid fever remains a persistent public health challenge, particularly in low- and middle-income nations.
  • Historically, routine vaccination has not been a widely implemented control strategy for typhoid.
  • Growing concerns about antimicrobial resistance and the burden of typhoid fever necessitate new control measures.

Purpose of the Study:

  • To inform about the World Health Organization's (WHO) revised global policy on typhoid vaccines issued in March 2018.
  • To highlight the role of typhoid conjugate vaccines (TCVs) in addressing the typhoid fever burden.
  • To outline considerations for implementing TCV vaccination strategies.

Main Methods:

  • The study is based on evidence-based recommendations from the WHO Strategic Advisory Group of Experts on immunization.
  • It considers the licensure of a new generation of TCVs.
  • It incorporates data on the typhoid fever burden and antimicrobial resistance.

Main Results:

  • The WHO issued a revised global policy recommending routine and catch-up vaccination with TCVs.
  • The policy suggests universal, risk-based, or phased vaccination strategies.
  • The availability of WHO-prequalified TCVs and Gavi funding makes vaccination a feasible option.

Conclusions:

  • Typhoid conjugate vaccines (TCVs) represent a realistic and recommended control strategy for typhoid fever.
  • Effective implementation requires integration with improved water and sanitation, enhanced surveillance, and appropriate antimicrobial treatment.
  • The new policy facilitates broader access to vaccination in affected countries.