[Acute renal failure of glomerular origin]
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Updated: Jan 28, 2026

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Published on: December 22, 2023
1Service de néphrologie, département hypertension artérielle, prévention et prise en charge des affections rénales et cardiovasculaires, Hôpital européen Georges-Pompidou, Assistance publique-Hôpitaux de Paris, université Paris-Descartes Paris, France.
Abstract:
Acute renal failure of glomerular origin. Glomerulopathies account for about 10% of acute kidney injury (AKI) in adults. They often require urgent care. The clinico-biological presentations are acute nephritic syndrome (GNA) and rapidly progressive glomerulonephritis. GNA combines an organic AKI with signs of sodium retention. The most commonly found germs are streptococci, staphylococci and Escherichia coli. Rapidly progressive glomerulonephritis is characterized by a renal failure that settles in a few weeks, with marked hematuria. Blood tests depend of the context but include complement study and ANCA. Histologically, extracapillary lesions are present with various immunoglobulin deposits.
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