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Updated: Jan 28, 2026

The Spared Nerve Injury SNI Model of Induced Mechanical Allodynia in Mice
Published on: August 18, 2011
[Treatment of mechanically induced nerve injuries]
Madeline T Kudibal1, Tim Kongsmark Weltz, Morten Bo Larsen
1madelinetherese@hotmail.com.
Abstract:
Peripheral nerve injury can result in significant morbidity. The gold-standard treatment is currently end-to-end suture and is possible by mobilisation of nerve ends in cases with segmental nerve loss up to 1 cm. In cases of defects above 1 cm nerve autograft is the gold-standard treatment. To avoid donor site morbidity alternative procedures can be used, including conduits, nerve transfers and end-to-side suture. The purpose of this review is to create an overview of the currently available treatments of peripheral nerve injury and the clinical management of patients.
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