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Updated: Jan 28, 2026

A Protocol for the Production of Gliadin-cyanoacrylate Nanoparticles for Hydrophilic Coating
Published on: July 8, 2016
Nanoscopic hydrophilic/hydrophilic phase-separation well below the LCST of polyphosphoesters
Johannes Hunold1, Thomas Wolf, Frederik R Wurm
1Institut für Chemie, Martin-Luther-Universität Halle-Wittenberg, Von-Danckelmann-Platz 4, 06120 Halle (Saale), Germany. dariush.hinderberger@chemie.uni-halle.de.
Abstract:
The complex phase separation process of thermoresponsive polyphosphoesters (PPEs) with an identical side-group structure but different copolymer compositions is characterized by electron paramagnetic resonance (EPR) spectroscopy. In water these PPEs show LCST-type behavior, in which water-rich and slightly polymer-enriched nanoscopic regions are highly water swollen, and nanoscopic inhomogeneities with the lowest polarity contrast measured so far develop 8 °C below the macroscopic cloud point.
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