Related Experiment Video
Updated: Jan 28, 2026

Orthopedic Robot-Assisted Femoral Neck System in the Treatment of Femoral Neck Fracture
Published on: March 3, 2023
The Role of Vitamin D in Pediatric Orthopedics
Michael P Horan1, Kevin Williams2, Daniel Hughes2
1Pediatric Orthopaedic Surgery, Palmetto Health-USC Orthopaedic Center, University of South Carolina, 14 Medical Park, Suite 200, Columbia, SC 29203, USA.
Insights
Vitamin D is crucial for pediatric bone health, impacting metabolism and skeleton development. Maintaining proper vitamin D, calcium, and phosphate levels prevents conditions like rickets and fractures in children.
Area of Science:
- Pediatric Orthopedics
- Bone Metabolism
- Nutritional Science
Background:
- Vitamin D is essential for pediatric bone health.
- Imbalances in vitamin D, calcium, and phosphate affect skeletal development.
- Pathologic conditions like rickets and fractures can arise from these imbalances.
Purpose of the Study:
- To review the role of vitamin D in pediatric orthopedics.
- To highlight current research directions concerning vitamin D in pediatric bone health.
Main Methods:
- Literature review of vitamin D's role in pediatric bone metabolism.
- Analysis of conditions affected by vitamin D deficiency.
- Identification of emerging research areas in pediatric orthopedic nutrition.
Main Results:
- Vitamin D significantly influences pediatric bone metabolism and skeletal development.
- Disruptions in vitamin D homeostasis can lead to rickets and fractures.
- Research is focusing on optimizing vitamin D status for pediatric orthopedic care.
Conclusions:
- Adequate vitamin D is vital for healthy pediatric skeletal growth.
- Understanding vitamin D's role is key to managing pediatric orthopedic conditions.
- Further research will refine therapeutic strategies for vitamin D management in children.
Abstract:
Understanding the role of vitamin D is an important component of the proper care of the pediatric orthopedic patient. Vitamin D is an essential component of bone metabolism in the growth and development of the pediatric skeleton, which can be acutely affected by changes to the body's vitamin D, calcium, and phosphate levels, resulting in pathologic conditions such as rickets or fractures. This article reviews the main areas in which vitamin D relates to pediatric orthopedics and highlights some of the areas where future research is being directed.
Related Concept Videos
Role of Skin in Vitamin D Synthesis
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
Role of Vitamins in Maintaining Bone Health
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamins
Mineral, Vitamin and Water Absorption
Pharmacokinetics in Pediatric Patients: Drug Excretion
Pharmacokinetics in Pediatric Patients: Drug Distribution

