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Updated: Jan 27, 2026

Manganese Oxide Nanoparticle Synthesis by Thermal Decomposition of ManganeseII Acetylacetonate
Published on: June 18, 2020
Directing-Group-Assisted Manganese-Catalyzed Cyclopropanation of Indoles
Pratip K Dutta1, Jyoti Chauhan1, Mahesh Kumar Ravva2
1Department of Chemistry, School of Natural Sciences , Shiv Nadar University , Dadri, Chithera , Gautam Budh Nagar , UP 201314 , India.
Abstract:
The first manganese-catalyzed cyclopropanation of indoles is reported in moderate to excellent yield with methyl-2-diazo-2-arylacetates. This new strategy involved acetyl (COCH3) as the directing group and exhibited exceptional functional group tolerance. In the absence of stereodirecting groups the desired products were obtained as a mixture of diastereomers (7:3 → 8:2). Control experiments and DFT studies elucidated the probable pathway for the formation of cyclopropane-fused indole product. Deacetylation of the final products afforded both C3-substituted NH-indoles.
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