Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

System of Memory01:23

System of Memory

7.3K
Memory is categorized into three major systems: sensory memory, short-term memory (STM), and long-term memory (LTM). These systems differ in their capacity and the duration for which they can hold information. Sensory memory captures raw sensory input from the environment, holding it for just a few seconds or less. For example, on hearing a brief, loud sound, like a car horn honking, the sound seems to linger in the mind for a moment even after it stops. This is an instance of sensory memory...
7.3K
Working Memory01:24

Working Memory

852
Working memory refers to a combination of components, including short-term memory and attention, that allow an individual to hold information temporarily as we perform cognitive tasks. It is an essential cognitive function that enables the execution of complex tasks such as problem-solving, comprehension, and reasoning. Unlike short-term memory, which simply involves the storage of information for a brief period, working memory involves the active manipulation and processing of this...
852
Long-Term Memory01:18

Long-Term Memory

669
Long-term memory is a relatively permanent type of memory, capable of storing vast amounts of information over extended periods. Its storage capacity is generally considered unlimited.
Long-term memory can be categorized into two primary types: explicit and implicit memory. Explicit memory, also known as declarative memory, involves the conscious recollection of information that we deliberately try to remember, recall, and articulate. This type of memory encompasses specific facts, events, and...
669
Traumatic Memory01:20

Traumatic Memory

566
Emotionally traumatic events often lead to memories that are exceptionally vivid and enduring, sometimes persisting with remarkable clarity throughout an individual's life. A classic example of this phenomenon is a person who survives a car accident. Even years later, they may recall every detail of the event with startling accuracy — the screeching of the tires, the jarring impact, and the acrid smell of burning rubber. Such vividness contrasts sharply with how an individual...
566
Repressed Memory01:16

Repressed Memory

511
Repressed memories are a psychological phenomenon where memories of traumatic events are unconsciously blocked from a person's awareness. This process occurs as a defense mechanism, protecting the mind from the emotional impact of distressing or painful experiences. For example, a person who has experienced childhood trauma may grow up with no conscious recollection of the event. In such cases, the memories are thought to be buried deep within the subconscious, inaccessible to the conscious...
511
Immunological Memory01:23

Immunological Memory

16.7K
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
16.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Response to Barnawi et al., "Bullous pemphigoid in the era of immunotherapy: Implications for treatment algorithms".

Journal of the American Academy of Dermatology·2026
Same author

Pustular Dermatoses. Part II. Infectious, Genetic, and Transient Neonatal.

Journal of the American Academy of Dermatology·2026
Same author

Pustular Dermatoses. Part I. Inflammatory and Autoimmune.

Journal of the American Academy of Dermatology·2026
Same author

US expert opinions on the treatment of bullous pemphigoid based on guidelines from the European Academy of Dermatology and Venereology.

Journal of the American Academy of Dermatology·2026
Same author

The ancestral haplotype of P2RX5 yields a B-cell surface marker and a multi-lineage immunotherapy target.

bioRxiv : the preprint server for biology·2026
Same author

Nanoparticle Immunoadjuvant Complexes Augment Germinal Center Responses to Vaccination.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Related Experiment Video

Updated: Jan 27, 2026

A Real-world What-Where-When Memory Test
09:13

A Real-world What-Where-When Memory Test

Published on: May 16, 2017

12.1K

What B cell memories are made of.

Mary M Tomayko1, David Allman2

  • 1The Department of Dermatology, Yale University, New Haven, CT 06511, United States.

Current Opinion in Immunology
|March 13, 2019
PubMed
Summary

Memory B cells are key to humoral immunity, providing long-lived protection. Emerging evidence reveals diverse pathways and functions among these critical immune cells.

More Related Videos

Shape Memory Polymers for Active Cell Culture
10:53

Shape Memory Polymers for Active Cell Culture

Published on: July 4, 2011

13.9K
In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells
10:26

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells

Published on: January 20, 2019

13.1K

Related Experiment Videos

Last Updated: Jan 27, 2026

A Real-world What-Where-When Memory Test
09:13

A Real-world What-Where-When Memory Test

Published on: May 16, 2017

12.1K
Shape Memory Polymers for Active Cell Culture
10:53

Shape Memory Polymers for Active Cell Culture

Published on: July 4, 2011

13.9K
In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells
10:26

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells

Published on: January 20, 2019

13.1K

Area of Science:

  • Immunology
  • Cell Biology

Background:

  • Memory B cells are crucial for long-term humoral immunity and protection against pathogens.
  • High-affinity antigen-specific B cell receptors characterize many memory B cells.
  • These cells are a vital source of long-lived plasma cells that secrete protective antibodies.

Purpose of the Study:

  • To review the foundational concepts and early studies of B cell memory.
  • To discuss the diverse cellular pathways and molecular events in memory B cell development.
  • To explore the varied functional attributes and subpopulations of memory B cells.

Main Methods:

  • Review of existing literature on B cell memory.
  • Analysis of conceptual ideas and early experimental studies.
  • Discussion of current approaches for characterizing memory B cell subpopulations.

Main Results:

  • Not all memory B cells arise through identical cellular pathways.
  • Different memory B cell subsets exhibit distinct functions upon reactivation.
  • Some memory B cells differentiate into plasma cells, while others produce more memory cells.

Conclusions:

  • Memory B cell heterogeneity is a significant aspect of humoral immunity.
  • Understanding diverse memory B cell pathways and functions is essential for effective immune responses.
  • Further research into characterizing these subpopulations is ongoing.