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Updated: Jan 27, 2026

In Vivo Calcium Imaging of Dorsal Root Ganglia Neurons' Response to Somatic and Visceral Stimuli
Published on: March 1, 2024
Imaging of Somatic Ca2+ Transients in Differentiated Human Neurons
Irena Vertkin1, Dalit Ben-Yosef2
1Department of Cell and Developmental Biology, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel. tallestra@gmail.com.
Abstract:
Calcium is a major regulator of neuronal activity and calcium signaling is critically important for normal neuronal function. Ca imaging is a well-established tool for studying neuronal function and ongoing spontaneous Ca2+ transients are a good indicator of neuronal maturity. There are various indicators available today, differing by their sensitivity, spectra, and loading method. Here we present a method for measurement of Ca2+ transients in neurons using two different Ca2+ indicators, Oregon Green BAPTA-1 and GCaMP6.
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