Indigenous Transmission of Mycobacterium africanum in Canada: A Case Series and Cluster Analysis
Arpita Chakravarti1, Hafid Soualhine2, Meenu Sharma2
1Department of Microbiology and Adult Infectious Diseases, Centre Hospitalier de l'Université de Montréal, Canada.
Abstract:
Mycobacterium africanum is an important cause of human tuberculosis and is found almost exclusively in West Africa. We identified a cluster of patients in Montreal, Canada, with M africanum disease that share identical genotypic signatures by mycobacterial interspersed repetitive unit-variable number tandem repeat (MIRU-VNTR) typing and a putative epidemiological link, thus providing evidence of possible local transmission of M africanum in Montreal over a 10-year period.
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