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Acinetobacter baumannii orofacial cellulitis: report of 2 cases
Thaís Dos Santos Fontes Pereira1, Denise Vieira Travassos2, Raissa Cristina Costa Silva1
1Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Minas Gerais, Brazil.
Multidrug-resistant Acinetobacter baumannii can cause severe orofacial cellulitis in pediatric patients, particularly those with compromised immune systems. This rare infection, often linked to oral lesions, can have fatal outcomes.
Area of Science:
- Infectious Diseases
- Pediatric Oncology
- Critical Care Medicine
Background:
- Acinetobacter baumannii (A. baumannii) is an opportunistic pathogen.
- Skin and soft tissue infections are rare manifestations of A. baumannii, typically linked to trauma.
Observation:
- Two pediatric cases of fatal orofacial cellulitis caused by A. baumannii are presented.
- Case 1: A 12-year-old male with acute promyelocytic leukemia developed A. baumannii cellulitis from an ulcerated lip lesion.
- Case 2: A 10-year-old male with Burkitt lymphoma developed severe mucositis and cellulitis due to A. baumannii.
Findings:
- Both patients had hemoculture-confirmed multidrug-resistant A. baumannii infections.
- The infections progressed rapidly, leading to fatal outcomes in both pediatric cases.
- A. baumannii was identified as the causative agent of severe cellulitis and necrosis.
Implications:
- A. baumannii should be considered in the differential diagnosis of severe cellulitis, especially in immunocompromised pediatric patients.
- Hospitalized pediatric patients with ulcerated oral lesions are at increased risk for A. baumannii infection.
- The findings highlight the potential for multidrug-resistant A. baumannii to cause severe, life-threatening infections in vulnerable pediatric populations.
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