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Randomized controlled trials on acupuncture for migraine: research problems and coping strategies
Heqing Chen1, Xiaoyu Zhang1, Xiaoyi Tang1
1Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China.
Annals of Translational Medicine
|April 30, 2019
Summary
This review highlights common issues in acupuncture clinical trials for migraine, focusing on trial design and data analysis. Recommendations are provided to improve the standardization and objective evaluation of acupuncture research.
Area of Science:
- Integrative and Complementary Medicine
- Clinical Trial Methodology
- Neurology
Background:
- Recent acupuncture clinical trials show promise but face challenges.
- Shortcomings in trial design and data processing hinder objective evaluation of acupuncture's efficacy and safety.
Purpose of the Study:
- To systematically review and summarize common problems in randomized controlled trials for acupuncture treatment of migraine.
- To identify and synthesize issues in trial design, data processing, and reporting.
Main Methods:
- Systematic review of randomized controlled trials evaluating acupuncture for migraine.
- Searched seven databases up to October 19, 2017.
- Meta-analysis to collect and synthesize common problems.
Main Results:
- Identified common shortcomings in trial design, statistical analysis, and article writing.
- Illustrated problems with specific examples.
Conclusions:
- Addressed probable causes for identified shortcomings in acupuncture trials.
- Provided recommendations to standardize trial design, data processing, and article reporting for objective evaluation.
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