Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fixed Action Patterns01:06

Fixed Action Patterns

17.6K
A fixed action pattern (FAP) is a specific, hard-wired sequence of behaviors that occurs in response to an external stimulus, called a sign stimulus. The behavior is “fixed” because it is essentially unchangeable—proceeding similarly across individuals of a species every time it occurs.
17.6K
CNS Stimulants: Cocaine, Amphetamines and Cannabinoids01:24

CNS Stimulants: Cocaine, Amphetamines and Cannabinoids

819
CNS stimulants, such as cocaine, amphetamines, and cannabinoids, have varying structures and mechanisms of action that lead to different therapeutic effects and side effects. Cocaine, with its molecular formula C17H21NO4, is a tropane alkaloid and a tertiary amino compound. It has two chemical forms: the hydrochloride salt and the "freebase." The former is in powder form, while the latter involves removing the hydrochloride salt to create a form that can be smoked. Cocaine exerts its...
819
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids01:21

Chemotherapy-Induced Nausea and Vomiting: Cannabinoids

719
Tetrahydrocannabinol (THC) is a phytocannabinoid that primarily interacts with the CB1 receptor, a type of G protein-coupled receptor (GPCR) predominantly in and around the chemoreceptor trigger zone (CTZ) and emetic center. THC also blocks the serotonin receptor activity in the dorsal vagal complex (DVC) by inhibiting serotonin release. THC exerts its anti-emetic effects through these interactions, which are beneficial for patients undergoing chemotherapy.
Two synthetic agonists of THC,...
719
Action Potential01:31

Action Potential

4.4K
Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
4.4K
Action Potential01:14

Action Potential

10.9K
Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
10.9K
Action Potentials01:41

Action Potentials

141.8K
Overview
141.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

International Union of Basic and Clinical Pharmacology. CXXII. Applying an objective evaluation to the status of class A orphan G protein-coupled receptors.

Pharmacological reviews·2026
Same author

Updated BJP guidelines for transparent and rigorous natural product research.

British journal of pharmacology·2026
Same author

The Concise Guide to PHARMACOLOGY 2025/26: Introduction and Other Protein Targets.

British journal of pharmacology·2025
Same author

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes.

British journal of pharmacology·2025
Same author

The Concise Guide to PHARMACOLOGY 2025/26: Transporters.

British journal of pharmacology·2025
Same author

The Concise Guide to PHARMACOLOGY 2025/26: Ion channels.

British journal of pharmacology·2025
Same journal

Fangchinoline alleviates hypertensive heart failure via PGC-1α/STAT6/PPARγ activation of mitophagy against ferroptosis.

British journal of pharmacology·2026
Same journal

The selective degradation of PDE4B shortform, using a PROTAC, leads to inhibition of several hallmarks of cancer in HCT116 cells.

British journal of pharmacology·2026
Same journal

Immune checkpoint inhibitor-induced arrhythmias: Mechanistic insights from clinical and preclinical studies.

British journal of pharmacology·2026
Same journal

Leflunomide-inhibited STAT1 activity ameliorates intramuscular M1 macrophage infiltration and promotes muscle regeneration in Duchenne muscular dystrophy.

British journal of pharmacology·2026
Same journal

Pharmacological activation of NO-cGMP signalling attenuates metabolic dysfunction-associated steatohepatitis.

British journal of pharmacology·2026
Same journal

Inhibition of kynurenine 3-monooxygenase (KMO) reduces fentanyl and sucrose intake and relapse-like behaviour in rats.

British journal of pharmacology·2026
See all related articles

Related Experiment Video

Updated: Jan 25, 2026

Tobacco Hornworm as an Insect Model System for Cannabinoid Pre-clinical Studies
05:25

Tobacco Hornworm as an Insect Model System for Cannabinoid Pre-clinical Studies

Published on: December 29, 2021

2.9K

Cannabinoids and their actions: An update.

Stephen P H Alexander1, Francisco Molina-Holgado2

  • 1School of Life Sciences, University of Nottingham, Nottingham, UK.

British Journal of Pharmacology
|April 30, 2019
PubMed
Summary
This summary is machine-generated.

This research explores the complex world of cannabinoid research, focusing on recent advancements and their implications. Discover the latest findings in the field of cannabinoids and their therapeutic potential.

More Related Videos

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time
06:05

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time

Published on: February 19, 2021

1.6K
Updated Protocol for the Assembly and Use of the Minibioreactor Array (MBRA)
09:38

Updated Protocol for the Assembly and Use of the Minibioreactor Array (MBRA)

Published on: September 5, 2025

862

Related Experiment Videos

Last Updated: Jan 25, 2026

Tobacco Hornworm as an Insect Model System for Cannabinoid Pre-clinical Studies
05:25

Tobacco Hornworm as an Insect Model System for Cannabinoid Pre-clinical Studies

Published on: December 29, 2021

2.9K
The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time
06:05

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time

Published on: February 19, 2021

1.6K
Updated Protocol for the Assembly and Use of the Minibioreactor Array (MBRA)
09:38

Updated Protocol for the Assembly and Use of the Minibioreactor Array (MBRA)

Published on: September 5, 2025

862

Area of Science:

  • Pharmacology
  • Neuroscience
  • Biochemistry

Background:

  • The 8th European Workshop on Cannabinoid Research convened experts to discuss the latest findings in the field.
  • This themed section highlights cutting-edge research on the endocannabinoid system and phytocannabinoids.

Discussion:

  • Key discussions revolved around the therapeutic applications of cannabinoids for various medical conditions.
  • Emerging research on novel cannabinoid derivatives and their mechanisms of action was presented.

Key Insights:

  • Cannabinoids show significant promise in managing pain, inflammation, and neurological disorders.
  • Understanding the intricate interactions within the endocannabinoid system is crucial for developing effective treatments.

Outlook:

  • Future research will likely focus on personalized cannabinoid therapies and addressing regulatory challenges.
  • Continued exploration of non-psychoactive cannabinoids may unlock new therapeutic avenues.