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The evaluation of cardiac functions according to chronic obstructive pulmonary disease groups
Onur Yazici1, Sule Tas Gulen1, Ufuk Eryilmaz2
1Department of Chest Diseases, School of Medicine, Adnan Menderes University, Aydin, Turkey.
Insights
Echocardiography revealed significant differences in right and left ventricular function in chronic obstructive pulmonary disease (COPD) patients. Increased pulmonary arterial pressure and cardiovascular comorbidities were linked to symptoms in severe COPD groups.
Area of Science:
- Cardiology
- Pulmonology
- Medical Imaging
Background:
- Chronic obstructive pulmonary disease (COPD) significantly impacts cardiovascular health.
- Right and left ventricular dysfunction are common complications in COPD patients.
- Echocardiography (ECHO) is a key tool for assessing cardiac function.
Purpose of the Study:
- To compare right and left ventricular functions using ECHO in different COPD severity groups.
- To investigate the association between cardiac function and functional parameters in COPD.
- To identify potential cardiovascular risks in symptomatic COPD patients.
Main Methods:
- Retrospective analysis of ECHO data from 126 COPD patients (2015-2018).
- Correlation of ECHO findings with pulmonary function tests, 6-minute-walking test (6MWT), mMRC, CAT, and BODE scores.
- Categorization of patients into COPD assessment stages (A, B, C, D).
Main Results:
- Significant differences in systolic pulmonary arterial pressure (sPAP) and left ventricle end-systolic diameter (LVEF) across COPD groups (p<0.001 and p=0.004).
- Elevated sPAP observed in COPD groups D and B; lowest LVEF in group D.
- Cardiovascular diseases (CVD) and pulmonary hypertension (PH) were most prevalent in COPD groups D and B.
Conclusions:
- Symptomatic COPD patients in groups B and D may experience exacerbated symptoms due to increased pulmonary arterial pressure (PAP) and cardiovascular comorbidities.
- Early and comprehensive cardiovascular evaluation is crucial for managing COPD patients.
- Echocardiography plays a vital role in detecting and monitoring cardiac complications in COPD.
Abstract:
Objectives: We aimed to compare right and left ventricular functions by echocardiography (ECHO) according to chronic obstructive pulmonary disease (COPD) groups, and to determine their associations with functional parameters.Methods: Data of patients with COPD who underwent ECHO between 2015 and 2018 were analyzed retrospectively. The results of pulmonary function tests, 6-minute-walking test (6MWT), Modified Medical Research Council (mMRC), COPD assessment test (CAT), and BODE scores were recorded together with ECHO results showing right and left ventricular functions.Results: 126 COPD patients were evaluated. Of these, 37.3% was in group A, 28.6% in group B, 12.7% in group C, and 21.4% in group D. Most common comorbidities were cardiovascular diseases (CVD) and pulmonary hypertension (PH); these were most frequently seen in groups D and B. Regarding ECHO parameters, differences were present among groups in systolic pulmonary arterial pressure (sPAP) and left ventricle end-systolic diameter (LVEF) (p < 0.001 and 0.004, respectively). sPAP was highest in groups D and B whereas LVEF was lowest in group D.Conclusion: Our results suggest that patients' symptoms in symptomatic COPD groups B and D might be related to increased PAP and concomitant cardiovascular comorbidities. Therefore, a detailed cardiovascular investigation should be performed from early stages in COPD.
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