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Updated: Jan 25, 2026
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Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
Published on: February 12, 2018
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Nonsupine Positioning after Macular Hole Surgery: A Prospective Multicenter Study.
Birger Lindtjørn1, Jørgen Krohn2, Dordi Austeng3
1Department of Ophthalmology, Stavanger University Hospital, Stavanger, Norway.
Ophthalmology. Retina
|May 3, 2019
Summary
Nonsupine positioning after macular hole surgery achieved a 99.5% closure rate. This study found that strict adherence to positioning was not necessary for successful outcomes in macular hole (MH) repair.
Area of Science:
- Ophthalmology
- Retinal Surgery
- Surgical Outcomes
Background:
- Macular holes (MHs) are a common cause of vision loss.
- Surgical repair of MHs often involves specific postoperative positioning to promote closure.
- The necessity of strict, prolonged nonsupine positioning requires further investigation.
Purpose of the Study:
- To evaluate the postoperative closure rate of full-thickness macular holes (MHs) after nonsupine positioning.
- To investigate the correlation between postoperative positioning compliance and MH closure rate.
Main Methods:
- Prospective, multicenter study of patients undergoing primary MH surgery.
- Pars plana vitrectomy with internal limiting membrane peeling and sulfur hexafluoride gas tamponade.
- 3 to 5 days of nonsupine positioning with a device monitoring supine time for 24 hours.
Main Results:
- A total of 205 participants were included; 202 of 203 MHs closed (99.5% closure rate).
- Median supine positioning time in the first 24 hours was 28 seconds.
- A correlation between positioning compliance and closure rate could not be established due to the high success rate.
Conclusions:
- Short-term nonsupine positioning following pars plana vitrectomy with internal limiting membrane peeling achieves a very high MH closure rate.
- Face-down positioning was not necessary to achieve excellent closure rates in this study.
- These findings suggest a potential relaxation of postoperative positioning protocols for MH surgery.
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