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Compressed Sensing 3D-GRASE for faster High-Resolution MRI.

A Cristobal-Huerta1, D H J Poot1,2, M W Vogel3

  • 1Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands.

Magnetic Resonance in Medicine
|May 3, 2019
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Summary
This summary is machine-generated.

Compressed sensing parallel imaging (CSPI) on 3D-GRASE MRI accelerates scan times and reduces SAR. Variable density Poisson-disc sampling patterns improve image quality for high-resolution 3D MRI.

Keywords:
CSEcho planar imagingFast spin echoGRASESARcompressed sensing and parallel imaging

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Area of Science:

  • Medical Imaging
  • Magnetic Resonance Imaging
  • Image Reconstruction

Background:

  • High-resolution 3D MRI is crucial for visualizing small anatomical structures.
  • Long acquisition times and high specific absorption rate (SAR) limit clinical applications of high-resolution 3D MRI.

Purpose of the Study:

  • To accelerate high-resolution 3D MRI acquisition using compressed sensing and parallel imaging (CSPI) on a 3D-GRASE sequence.
  • To compare the performance of CSPI 3D-GRASE with CSPI 3D-FSE sequences.

Main Methods:

  • Investigated various k-space sampling patterns, including variable density (VD) Poisson-disc and VD pseudo-random Gaussian.
  • Utilized Bloch simulations to evaluate sampling pattern coherence and image resolution (FWHM).
  • Conducted phantom and in vivo (knee, brain) experiments to assess image quality, SNR, SAR, and acquisition time.

Main Results:

  • VD Poisson-disc sampling patterns demonstrated the lowest coherence.
  • CSPI 3D-GRASE significantly reduced acquisition time (up to 43%) and SAR (up to 45%) compared to CSPI 3D-FSE.
  • Image quality was preserved with CSPI 3D-GRASE.

Conclusions:

  • CSPI 3D-GRASE offers a faster and safer alternative to CSPI 3D-FSE for high-resolution 3D MRI.
  • The choice of sampling pattern critically impacts image quality in CSPI 3D-GRASE acquisitions.