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Quantifying Retinal Area in Ultra-Widefield Imaging Using a 3-Dimensional Printed Eye Model.
Luke Nicholson1, Clara Vazquez-Alfageme2, Monica Clemo2
1National Institute for Health Research Moorfields Biomedical Research Centre, Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, United Kingdom; Western Sussex National Health Service Foundation Trust, Worthing, United Kingdom.
Ophthalmology. Retina
|May 4, 2019
Summary
Image distortion in ultra-widefield imaging increases with angular location, not eye length. These findings on enlargement factors can improve area measurements in clinical practice.
Area of Science:
- Ophthalmology
- Medical Imaging
- Optical Engineering
Background:
- Ultra-widefield imaging is crucial for retinal examination.
- Software correction aims to minimize image distortion.
- Understanding residual distortion is essential for accurate measurements.
Purpose of the Study:
- To evaluate image distortion in ultra-widefield imaging across different axial lengths.
- To quantify the enlargement factor based on angular location.
- To assess the effectiveness of software correction in mitigating distortion.
Main Methods:
- Used 3D-printed model eyes with varying axial lengths (22, 24, 26 mm).
- Imaged models using Optos 200TX and applied V2 Vantage Pro software correction.
- Measured inter-ring areas using ImageJ to calculate enlargement factors.
Main Results:
- Enlargement factor increased with angular location, reaching 1.9 at the equator.
- Axial length did not significantly impact the enlargement factor (P=0.9512).
- Significant distortion persisted at the anterior equator despite software correction.
Conclusions:
- Image enlargement in ultra-widefield imaging is dependent on angular location, not axial length.
- Calculated enlargement factors can enhance the accuracy of area measurements in clinical settings.
- Awareness of peripheral distortion is necessary for precise interpretation of ultra-widefield images.
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