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Updated: Jan 25, 2026
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Author Spotlight: Quantifying Pain Experience – An Illustrative Approach Using the Pain Body Diagram
Published on: July 7, 2023
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ACR Appropriateness Criteria® Right Upper Quadrant Pain.
, Christine M Peterson1, Michelle M McNamara2
1Penn State Health, Hershey, Pennsylvania.
Summary
Right upper quadrant pain evaluation is clarified using imaging guidelines for suspected biliary disease and cholecystitis. This review details appropriate imaging procedures for accurate diagnosis.
Area of Science:
- Radiology
- Gastroenterology
- Clinical Medicine
Background:
- Right upper quadrant pain is a common, yet often nonspecific, clinical presentation.
- Acute cholecystitis is frequently diagnosed by excluding other conditions.
- Various imaging modalities are available for evaluating right upper quadrant pain.
Purpose of the Study:
- To review recommended imaging evaluations for right upper quadrant abdominal pain.
- To clarify appropriate utilization of imaging procedures in suspected biliary disease, acute cholecystitis, and acalculous cholecystitis.
- To provide evidence-based guidelines for clinical scenarios involving right upper quadrant pain.
Main Methods:
- Focuses on the American College of Radiology Appropriateness Criteria.
- Utilizes an extensive analysis of peer-reviewed medical literature.
- Applies the RAND/UCLA Appropriateness Method and GRADE methodology.
- Incorporates expert opinion when evidence is lacking or equivocal.
Main Results:
- Provides a framework for selecting appropriate imaging for right upper quadrant pain.
- Addresses specific clinical scenarios including biliary disease and cholecystitis.
- Offers guidance on the judicious use of diagnostic imaging.
Conclusions:
- Appropriate utilization of imaging procedures is crucial for diagnosing right upper quadrant pain.
- Evidence-based guidelines aid in selecting the most suitable imaging tests.
- Multidisciplinary expert consensus informs recommendations for complex cases.
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