[THE BIOMARKERS OF MYOCARDIAL DAMAGE AND THEIR ROLE IN THE PROGRESSION OF HEART FAILURE (REVIEW)]

Despite the success achieved in the study and treatment of chronic heart failure, this syndrome still remains one of the most difficult and predictable unreliable pathologies. Moreover, in recent years there has been a tendency of growth of such patients. Based on the above, the attention of scientists focuses on new concepts that involve the study of new biomarkers of cardiac damage and the definition of their role in the progression of heart failure. Based on studies conducted by numerous authors, the paper analyzes the importance of new biomarkers of myocardial damage in the development of heart failure. The manuscript describes biomarkers of damage (troponin T, galectin 3, lipocalin, Cystatin C): nature: the causes and mechanisms of their growth, increase and activity. Biomarkers of myocardial damage are shown to have diagnostic and high predicted values. Their temporary definition provides additional information for stratifying the risks of possible complications. It also gives us the opportunity to allocate patients with high risks in a timely manner and eliminate possible adverse complications.